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Health Benefits and Risks of Fermented Foods -The PIMENTO Initiative

Todorovic, Smilja; ...; Laranjo, Marta; ...; Vergères, Guy

Worldwide, fermented foods (FF) are recognized as healthy and safe. Despite the rapid increase of research papers, there is a lack of systematic evaluation of the health benefits and risks of FF. The COST Action CA20128 “Promoting innovation of fermented foods” (PIMENTO) aims to provide a comprehensive assessment on the available evidence by compiling a set of 16 reviews. Seven reviews will cover clinical and b...


Characterization of Plasma Labile Heme in Hemolytic Conditions

Gouveia, Zélia; Carlos, Ana Rita; Yuan, Xiaojing; Aires-da-Silva, Frederico; Stocker, Roland; J. Maghzal, Ghassan; Leal, Sónia S.; Gomes, Cláudio M.

Extracellular hemoglobin (Hb), a byproduct of hemolysis, can release its prosthetic heme groups upon oxidation. This produces metabolically active heme that is exchangeable between acceptor proteins, macromolecules and low molecular weight ligands, termed here labile heme. As it accumulates in plasma labile heme acts in a pro-oxidant manner and regulates cellular metabolism while exerting pro-inflammatory and c...


SERR spectroelectrochemical study of cytochrome cd1 nitrite reductase co-immobi...

Silveira, Célia M.; Quintas, Pedro O.; Moura, Isabel; Moura, José J. G.; Hildebrandt, Peter; Almeida, M. Gabriela; Todorovic, Smilja

"Cytochrome cd1 nitrite reductases (cd1NiRs) catalyze the one-electron reduction of nitrite to nitric oxide. Due to their catalytic reaction, cd1NiRs are regarded as promising components for biosensing, bioremediation and biotechnological applications. Motivated by earlier findings that catalytic activity of cd1NiR from Marinobacter hydrocarbonoclasticus (Mhcd1) depends on the presence of its physiological redo...


High ionicity ionic liquids (HIILs): comparing the effect of ethylsulfonate and...

Oliveira, Filipe S.; Pereiro, Ana B.; Araújo, João M. M.; Bernardes, Carlos E. S.; Lopes, J N Canongia; Todorovic, Smilja; Feio, Gabriel

The subject of ionicity has been extensively discussed in the last decade, due to the importance of understanding the thermodynamic and thermophysical behaviour of ionic liquids. In our previous work, we established that ionic liquids' ionicity could be improved by the dissolution of simple inorganic salts in their milieu. In this work, a comparison between the thermophysical properties of two binary systems of...


Purification and Preliminary Characterization of Tetraheme Cytochrome and Adeny...

López-Cortés, Alejandro; Bursakov, Sergey; Figueiredo, Angelo; Thapper, Anders E.; Todorovic, Smilja; Moura, José J. G.; Ollivier, Bernard

Bioinorganic Chemistry and Applications Volume 3 (2005), Issue 1-2, Pages 81-91; Two proteins were purified and preliminarily characterized from the soluble extract of cells (310 g, wet weight) of the aminolytic and peptidolytic sulfate-reducing bacterium Desulfovibrio (D.) aminophilus DSM 12254. The iron-sulfur flavoenzyme adenylylsulfate (adenosine 5"-phosphosulfate, APS)reductase, a key enzyme in the microbi...


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