16 documents found, page 1 of 2

Hemotropic mycoplasmas in bats from forest fragments, state of Paraná, southern...

The order Chiroptera is the second largest group of mammals with bats being identified as reservoir of several viral zoonoses, although, little is known about their role in other groups of pathogens, including hemotropic Mycoplasma spp. To date, hemoplasma species have been found infecting several species of bats with high genetic diversity between 16S rRNA gene sequences. On this study, we aimed to identify th...

Mass Treatment does not reduce the prevalency of parasites in Guarani indigenou...

The high frequency of intestinal parasites is favored by environmental and socio-cultural conditions of indigenous populations, and is still a neglected public health problem. Mass administration of broad-spectrum drugs aims to reduce the prevalence and intensity of the infections. The prevalence of intestinal parasites in school-children in an indigenous Guarani village in southern Brazil, was evaluated before...

Suprahyoid muscle activity in patients with chagasic megaesophagus

Differential expression of proteins in genetically distinct Trypanosoma cruzi s...

Background Trypanosoma cruzi, a hemoflagellate protozoan parasite and the etiological agent of Chagas disease (CD), exhibits great genetic and biological diversity. Infected individuals may present clinical manifestations with different levels of severity. Several hypotheses have been proposed to attempt to correlate the diversity of clinical signs and symptoms to the genetic variability of T. cruzi. This work ...

Variation in susceptibility to benznidazole in isolates derived from Trypanosom...

In this work, the susceptibility to benznidazole of two parental Trypanosoma cruzi strains, Colombian and Berenice-78, was compared to isolates obtained from dogs infected with these strains for several years. In order to evaluate the susceptibility to benznidazole two groups of mice were infected with one of five distinct populations isolated from dogs as well as the two parental strains of T. cruzi. The first...

Trypanosoma cruzi I and IV stocks from Brazilian Amazon are divergent in terms ...

Background: In the Brazilian Amazon, clinical and epidemiological frameworks of Chagas disease are very dissimilar in relation to the endemic classical areas of transmission, possibly due to genetic and biological characteristics of the circulating Trypanosoma cruzi stocks. Twenty six T. cruzi stocks from Western Amazon Region attributed to the TcI and TcIV DTUs were comparatively studied in Swiss mice to test ...

Usefulness of the polymerase chain reaction for monitoring cure of mice infecte...

The capacity of the polymerase chain reaction (PCR) to detect the DNA of Trypanosoma cruzi was evaluated in 90 blood samples from BALB/c mice infected with T. cruzi cloned stocks of genotypes 19 and 20 (T. cruzi I) and 39 and 32 (T. cruzi II), and treated with benznidazole. The results from the fresh blood examination, hemoculture, and ELISA allowed to group the treated animals into: cured (TC), dissociated (DI...

Fase crônica cardíaca fibrosante da Tripanossomíase cruzi experimental no cão.

De acordo com os trabalhos publicados ate o momento, o cão esta sendo considerado, com ressalvas, como modelo ideal para o estudo da fase aguda e crônica indeterminada da tripanossomiase cruz jl 2 3 4 5 6 7 14 15 18 19 20 21 24 Os requisitos para um modelo ideal, estabelecidos pelo Comite de Doenca de Chagas do Programa Especial de Treinamento e Pesquisa de Doenças Parasitarias da Organização Mundial de Saude25...

Trypanosoma cruzi : sensitivity of the polymerase chain reaction for detecting ...

The polymerase chain reaction showed high sensitivity for detecting Trypanosoma cruzi in the blood of mice, independent of clonal genotype (19, 20—T. cruzi I; 32, 39—T. cruzi II) or phase of the infection (acute or chronic).

Impact of Trypanosoma cruzi clonal evolution on its biological properties in mice.

Twenty Trypanosoma cruzi stocks attributed to the 19, 20, 39, and 32 clonal genotypes were comparatively studied in BALB/c mice during the acute and chronic phases of the infection to test the working hypothesis that T. cruzi clonal structure has a major impact on its biological properties. Fourteen parameters were assayed: (1) infectivity; (2) prepatent period; (3) patent period; (4) maximum of parasitemia; (5...