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Managing Stress in the Helping Professions: Clinical Trials with Teachers and N...

Candeias, Adelinda; Ambriz, Mario; Tomás, Mariana; Galindo, Edgar

This study investigated the effectiveness of the Optimistic Stress Management Program—a cognitive-behavioral intervention—in mitigating occupational stress among nurses (N=8) and teachers (N=10). Both professions are identified as highly vulnerable to stress and burnout due to emotional and organizational demands.The quasi-experimental intervention used a non-concurrent multiple baseline design and incorporated...


Vaginal Sheets with Thymbra capitata Essential Oil for the Treatment of Bacteri...

Tomás, Mariana; Sousa, Lúcia G. V.; Oliveira, Ana Sofia; Gomes, Carolina P.; Palmeira-de-Oliveira, Ana; Cavaleiro, Carlos; Salgueiro, Lígia; Cerca, Nuno

We aimed to incorporate Thymbra capitata essential oil (TCEO), a potent antimicrobial natural product against bacterial vaginosis (BV)-related bacteria, in a suitable drug delivery system. We used vaginal sheets as dosage form to promote immediate relief of the typical abundant vaginal discharge with unpleasant odour. Excipients were selected to promote the healthy vaginal environment reestablishment and bioadh...


Vaginal sheets with Thymbra capitata essential oil for the treatment of bacteri...

Tomás, Mariana; Sousa, Lúcia Filipa Guimarães Vieira; Oliveira, Ana Sofia; Gomes, Carolina P.; Palmeira-de-Oliveira, Ana; Cavaleiro, Carlos

We aimed to incorporate Thymbra capitata essential oil (TCEO), a potent antimicrobial natural product against bacterial vaginosis (BV)-related bacteria, in a suitable drug delivery system. We used vaginal sheets as dosage form to promote immediate relief of the typical abundant vaginal discharge with unpleasant odour. Excipients were selected to promote the healthy vaginal environment reestablishment and bioadh...


Synergistic effects of carvacrol, α-terpinene, γ-terpinene, ρ-cymene and linalo...

Sousa, Lúcia G. V.; Castro, Joana; Cavaleiro, Carlos; Salgueiro, Lígia; Tomás, Mariana; Palmeira-Oliveira, Rita; Martinez-Oliveira, José; Cerca, Nuno

Bacterial vaginosis (BV) is the most common vaginal infection affecting women worldwide. This infection is characterized by the loss of the dominant Lactobacillus community in the vaginal microbiota and an increase of anaerobic bacteria, that leads to the formation of a polymicrobial biofilm, mostly composed of Gardnerella spp. Treatment of BV is normally performed using broad-spectrum antibiotics, such as metr...


Synergistic effects of carvacrol, α-terpinene, γ-terpinene, ρ-cymene and linalo...

Sousa, Lúcia Filipa Guimarães Vieira; Castro, Joana Isabel Reis; Cavaleiro, Carlos; Salgueiro, Lígia; Tomás, Mariana; Palmeira-Oliveira, Rita

Bacterial vaginosis (BV) is the most common vaginal infection affecting women worldwide. This infection is characterized by the loss of the dominant Lactobacillus community in the vaginal microbiota and an increase of anaerobic bacteria, that leads to the formation of a polymicrobial biofilm, mostly composed of Gardnerella spp. Treatment of BV is normally performed using broadspectrum antibiotics, such as metro...


Isothiazolinones Quantification in Shampoo Matrices: A Matter of Method Optimiz...

Tomás, Mariana; Agonia, Ana Sofia; Borges, Lígia; Palmeira-de-Oliveira, Ana; Oliveira, Rita Palmeira de

Methylisothiazolinone (MI) is one of the most used preservatives in shampoos and also one of the most e ective. A preservative mixture known as Kathon CG is commercially available. It contains 5-chloro-2-methyl-4-isothiazolin-3-one (CMI) and 2-methyl-4-isothiazolin-3-one (MI) (3:1) and stabilizers. The aim of this study is to evaluate the influence of formulation factors in the quantification and stability of i...


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