2 documents found, page 1 of 1
Influence of external bacterial structures on the efficiency of photodynamic in...
Pereira, M. A.; Faustino, M. A. F.; Tomé, J. P. C.; Neves, M. G. P. M. S.; Tomé, A. C.; Cavaleiro, J. A. S.; Cunha, Â.; Almeida, A.The main targets of photodynamic inactivation (PDI) are the external bacterial structures, cytoplasmic membrane and cell wall. In this work it was evaluated how the external bacterial structures influence the PDI efficiency. To reach this objective 8 bacteria with distinct external structures were selected; 4 Gram-negative bacteria (Escherichia coli, with typical Gram-negative external structures; Aeromonas sal...
Porphyrins as Antimicrobial Photosensitizing Agents
Almeida, A.; Cunha, A.; Faustino, M. A. F.; Tomé, A. C.; Neves, M. G. P. M. S.The emergence of microbial resistance to many of the major classes of antimicrobial drugs is becoming an increasing problem in the clinic and environmental areas. As such, the discovery of drugs with novel modes of action will be vital to meet the threats created by the emergence of resistance. Photodynamic antimicrobial chemotherapy is receiving considerable attention for its potentialities as a new form of an...