27 documents found, page 1 of 3

Enhancing bacterial photodynamic inactivation through combined action of potass...

Infectious diseases remain a leading cause of death all around the world. Over the last three decades, the alarming and escalating emergence of antibiotic-resistant bacterial strains has caused some concern among the scientific community [1,2]. Photodynamic inactivation (PDI) emerges as an alternative for inactivating microorganisms, including bacteria [1–3]. The use of phthalocyanine (Pc) derivatives as photos...

Photodynamic inactivation of a RNA-virus model using water-soluble β-octa-Subst...

Among the various groups of microorganisms, viruses have generally a greater capacity for mutation, especially RNA viruses, as was demonstrated by SARS-CoV2 virus mutations. This high mutation rate promotes the development of their resistance to traditional antivirals and establishes the resistance behaviour in virus populations, decreasing their susceptibility to these drugs. In this context, the photodynamic ...

Exploring the reactivity of formylporphyrins with 3-(diethylamino)phenol. Synth...

The design of novel molecular structures with tunable photophysical properties is an important research field for many applications including optoelectronics, sensing and bioimaging. Porphyrin and rhodamine/rosamine derivatives are among the most studied and relevant chemosensors and imaging probes due to their attractive photophysical properties, such as high absorption coefficients and long emission wavelengt...

Phthalocyanine-functionalized magnetic silica nanoparticles as anion chemosensors

Anionic species are one of the most common pollutants in residual and freshwaters. The presence of anthropogenic anions in water drastically increases the toxicity to living beings. Here, we report the preparation of a new optical active material based on tri(tosylamino)phthalocyanines grafted to ferromagnetic silica nanoparticles for anion detection and removal. The new unsymmetrical phthalocyanines (Pcs) prov...

Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosens...

BODIPYs in antitumoral and antimicrobial photodynamic therapy: an integrating r...

Nowadays, both cancer and infections caused by antibiotic resistant microorganisms are problems that affect the entire planet. Phototherapy (namely photodynamic therapy (PDT) and photodynamic inactivation (PDI) of microorganisms) are an alternative method for the treatment of these diseases. That requires adequate photosensitizers and, in this sense, boron-dipyrromethenes (BODIPYs) have interesting properties t...

Phthalocyanine-sulfonamide conjugates: synthesis and photodynamic inactivation ...

Phthalocyanines bearing four or eight sulfonamide units were synthesized and their efficiency in the photodynamic inactivation of Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria was evaluated. Conjugates with simpler sulfonamide units (N,N-diethylbenzenesulfonamide, N-isopropylbenzenesulfonamide and N-(4-methoxyphenyl)benzenesulfonamide) caused stronger inactivation than thos...

Highly selective optical chemosensor for cyanide in aqueous medium

New cyanide selective chromogenic chemosensors based on metal-phthalocyanines containing four tosylamino groups were developed. These new receptors have high sensitivity for several anions (AcO−, F−, CN−, NO2−, H2PO4− and OH−) over other anions, such as: Br−, Cl−, NO3− and HSO4−. The experiments were conducted by UV–vis spectroscopy in DMSO and THF solutions. The selectivities were also checked in DMSO:water mi...

Octatosylaminophthalocyanine: a reusable chromogenic anion chemosensor

Detailed herein is the use of 2,3,9,10,16,17,23,24-octatosylaminophthalocyanine as a chromogenic chemosensor for anions. The host:guest complexes formed during the sensing event can be regenerated by acid treatment without loss of the sensing ability. This allows the phthalocyanine chemosensor to be reused. This system also responds in a colorimetric manner when exposed to the neutral solvent molecules, dimethy...

New porphyrin derivatives for phosphate anion sensing in both organic and aqueo...

New porphyrin-based anion receptors have been prepared from meso-tetrakis(pentafluorophenyl) porphyrin (TPPF20) and diamine derivatives. These receptors (compounds 1-3) interact preferentially with phosphate anions both in organic solutions and in basic aqueous media when coated on gold piezoelectric quartz crystals. A single crystal X-ray structure of the bis-HF complex of a imine derivative of 1 was obtained;...