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Evaluation of the Effect of Hemoglobin Concentration and of Mean Corpuscular Vo...

do Carmo, Anália; Queiroz, Ana Carolina; Escada Fontes, Fernanda; Mariano Pego, João; Tomé, Rui; Rodrigues, Fernando

Introduction: Diabetes mellitus (DM) is a metabolic disordercharacterized by chronic hyperglycemia and by the developmentof serious complications which determine the loss of thepatient’s quality of life. The evaluation of the glycemic controlin diabetic patients can be made based on the glycatedhemoglobin A1c (HbA1c) value. However, several studiesreported that anemia may limit the determination of HbA1c.Theref...


Multiple Myeloma IgM – a clinical case report

Santos, Bruno; Arez, Luísa; Taveira, Teresa; Palma, Santos; Tomé, Rui

The IgM monoclonal gammopathy can be associated with multiple pathologies namely lymphoproliferative conditions, multiple myeloma, solid tumours as well as benign conditions such as infections and monoclonal gammopathy of undetermined significance. The differential diagnosis is not always easy and it should follow clinical, laboratory and histopathologic criteria. To this purpose the authors present a clinical ...


An evaluation of the appropriateness of admissions to an Internal Medicine Serv...

Vieira, Nuno Bernardino; Rodriguez-Vera, Javier; Grade, Maria José; Arez, Luísa; Tomé, Rui; Santos, Carlos

Introduction: The Appropriateness Evaluation Protocol (AEP) is an instrument to measure the appropriateness of admissions based on criteria that permit classification of hospital admission as appropriate or inappropriate. It also could be used to quantify and evaluate the causes of inappropriate use of hospital resources. Objective: Evaluate the appropriateness of hospital admissions of patients admitted in a d...


Depression presenting as pernicious anaemia

Vieira, Nuno; Rodríguez-Vera, Javier; Arez, Luísa; Tomé, Rui

Pernicious anaemia is an uncommon cause of anaemia, caused by a deficiency of Vitamin B12. Independent of the aetiology, this deficiency may produce neurological alterations as well as psychiatric presentations.The case of a 42-year-old woman with a depressive syndrome, admitted to our department for severe anaemia, is presented in this article. Complementary diagnostic tests revealed a pernicious anaemia and t...


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