18 documents found, page 1 of 2

Lipedema: from women’s hormonal changes to nutritional intervention

Lipedema is a chronic disease of the subcutaneous adipose tissue that mostly affects women. The etiopathogenesis of the disease is still poorly understood. Lipedema typically develops after major hormonal changes, such as puberty, pregnancy, and menopause. Alongside genetic susceptibility, the pathophysiological mechanism involving hormonal changes is mostly linked to aberrantly expressed estrogen receptors in ...

Mediterranean diet and male fertility

Diet has an impact on male reproductive potential, but few studies have focused on the specific impact of food groups or dietary patterns on fertility. Male reproductive health, as indicated by improved semen parameters and increased chances of conceiving, is associated with the Mediterranean diet, while the Western diet is considered a risk factor for male infertility. The potential mechanisms that may explain...

The influence of metabolic profile of obese men on the severity of erectile dys...

Objective: To determine the prevalence of erectile dysfunction (ED) in metabolically healthy obese (MHO) individuals, and to compare ED severity and hypogonadism prevalence in MHO, metabolically unhealthy obese (MUO) and metabolically healthy non-obese individuals. Material and methods: ED patients (n=460) were evaluated by standardized protocol, that included clinical evaluation, abridged 5-item version of the...

Défice de Vitamina D: Comorbilidade da Obesidade Pediátrica ou Consequência do ...

Introdução: A hipovitaminose D está associada a compromisso ósseo e, na idade adulta, a um maior risco de desenvolvimento de doenças crónicas. São escassos os estudos portugueses relativos ao status de vitamina D e da massa óssea em idade pediátrica. Este trabalho teve como objetivo caracterizar o status de vitamina D e de massa óssea em crianças e adolescentes residentes na região do Porto e estudar a sua rela...

Characterization of TGF-β expression and signaling profile in the adipose tissu...

Transforming growth factor beta (TGF-β) plays an important role in the pathogenesis of obesity, influencing the release of inflammation mediators and promoting remodeling and collagen deposition in the adipose tissue (AT). In this context, this work aims to elucidate whether TGF-β and Smad-dependent or Smad-independent signaling pathways contribute to regional differentiation of AT in high-fat diet (HFD) and en...

Défice de Vitamina D: Comorbilidade da Obesidade Pediátrica ou Consequência do ...

Introduction: Hypovitaminosis D in childhood and adolescence is associated with reduced bone mass, as well as higher risk of chronic disease in adulthood. Studies regarding vitamin D status and bone health in the Portuguese paediatric population are rare. This study aimed to characterise vitamin D and bone mineralisation status in children and adolescents living in the Porto region and to analyse its relation w...

Characterization of TGF-ß expression and signaling profile in the adipose tissu...

Transforming growth factor beta (TGF-ß) plays an important role in the pathogenesis of obesity, influencing the release of inflammation mediators and promoting remodeling and collagen deposition in the adipose tissue (AT). In this context, this work aims to elucidate whether TGF-ß and Smad-dependent or Smad-independent signaling pathways contribute to regional differentiation of AT in high-fat diet (HFD) and en...

Expression of TGF-beta in different adipose tissue depots is singularly regulat...

Effects of high-fat diet, energy restriction, exercise and atorvastatin treatme...

Dieta híper -lipídica e restrição energética associam-se a um aumento da expres...