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Left-right side-specific endocrine signaling complements neural pathways to med...

Lukoyanov, NV; Watanabe, H; Carvalho, LS; Kononenko, O; Sarkisyan, D; Zhang, M; Andersen, MS; Lukoyanova, EA; Galatenko, V; Tonevitsky, A; Bazov, I

Brain injuries can interrupt descending neural pathways that convey motor commands from the cortex to spinal motoneurons. Here, we demonstrate that a unilateral injury of the hindlimb sensorimotor cortex of rats with completely transected thoracic spinal cord produces hindlimb postural asymmetry with contralateral flexion and asymmetric hindlimb withdrawal reflexes within 3 hr, as well as asymmetry in gene expr...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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