5 documents found, page 1 of 1
Real-world challenges in first-line treatment of metastatic EGFR-mutated non-sm...
Barreto, Inês; Figueiredo, Sara; Tonin, Fernanda S.; Vilariça, Ana Sofia; Hasmucrai, Direndra; Alves, Paula
Implications of a defined daily dose fixed database for drug utilization resear...
Abrantes, Catarina; Tonin, Fernanda S.; Reis-Pardal, Joana; Castel-Branco, Margarida; Furtado, Claudia; Figueiredo, Isabel V.Aims: Given the discrepancies between PDDs (prescribed daily doses) and DDDs (defined daily doses), we aimed to assess the extent of error in the results of an 18-year population-level study on statin utilization in Portugal. Methods: The Portuguese regulatory agency provided data for the period 2000–2018 on statin dispensing (C10AA). The DDDs were gathered from the ATC/DDD database. DDDs were calculated by the...
Reducing oral corticosteroids in severe asthma (ROSA Project): a nationwide Por...
Loureiro, Cláudia Chaves; Branco Ferreira, Manuel; Ferreira, Jorge; Lima, Ricardo; Marques, João; Sokolova, Anna; Tonin, Fernanda S.Introduction and objectives: We aimed to build a national consensus to optimize the use of oral corticosteroids (OCS) in severe asthma in Portugal. Material and methods: A modified 3-round Delphi including 65 statements (topics on chronic systemic corticotherapy, therapeutic schemes, asthma safety and monitoring) was performed via online platform (October-November 2019). A five-point Likert-type scale was used ...
Limitations and perceived delays for diagnosis and staging of lung cancer in Po...
Barata, Fernando; Fidalgo, Paula; Figueiredo, Sara; Tonin, Fernanda S.; Duarte-Ramos, FilipaBackground: We aimed to identify the perception of physicians on the limitations and delays for diagnosing, staging and treatment of lung cancer in Portugal. Methods: Portuguese physicians were invited to participate an electronic survey (Feb-Apr-2020). Descriptive statistical analyses were performed, with categorical variables reported as absolute and relative frequencies, and continuous variables with non-nor...
Analysis of completeness for spontaneous reporting of disease-modifying therapi...
Araujo, Ariane G. S.; Lucchetta, Rosa C. [UNESP]; Tonin, Fernanda S.; Pontarolo, Roberto; Borba, Helena H. L.; Wiens, AstridMade available in DSpace on 2021-06-25T10:55:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Introduction: Considering the need for effective postmarketing surveillance of disease-modifying therapies (DMTs) in multiple sclerosis (MS), we analyzed the potential of the spontaneous reports for safety signal detection, verifying the completeness of the reports in the FDA Adverse Event Reporting Sys...