3 documents found, page 1 of 1
Optimizing the use of systemic corticosteroids in severe asthma (ROSA II projec...
Marques, João; Duarte-Ramos, Filipa; Ferreira, Manuel Branco; Lima, Ricardo; Lopes, Cristina; Sokolova, Anna; Tonin, Fernanda StumpfAlthough the prevalence of severe asthma is not high (5-10% of patients), it is responsible for a large part of the overall disease burden and costs (50-60% of total costs), especially if the condition remains uncontrolled (which occurs in around 40% of cases). Currently, for patients without disease control or presenting frequent exacerbations despite optimal therapy, add-on treatments, traditionally long-acti...
Treatment interruption of biological drugs and tofacitinib in rheumatoid arthri...
Wiens, Astrid; Borba, Helena Hiemisch Lobo; Leonart, Letícia Paula; Tonin, Fernanda Stumpf; Steimbach, Laiza Maria; Araújo, Ariane Gonçalves Silva deThe aim of this study was to evaluate interruption of treatment with biological drugs and tofacitinib due to adverse events in patients with rheumatoid arthritis. A systematic review was performed in the electronic databases MEDLINE, Cochrane, Scopus, CRD, IPA, Lilacs and Scielo. Case reports addressing interruption of treatment due to any adverse event related to abatacept (ABA), adalimumab (ADA), anakinra (AN...
Comparação entre os métodos de detecção de Listeria monocytogenes simples e mul...
Souza, Vanessa Rodrigues de; Ferreira, Vinicius Lins; Pasquini-Netto, Harli; Tonin, Fernanda Stumpf; Abrahão, Wanda Moscalewski; Pontarolo, RobertoOs métodos de detecção para múltiplos patógenos têm sido usados para fornecer uma ampla faixa de detecção de microrganismos. Objetivou-se identificar os patógenos mais buscados nos métodos de detecção para L. monocytogenes e avaliar se existem diferenças nas taxas de sensibilidade e especificidade entre os métodos que buscaram identificar somente L. monocytogenes e os para múltiplos patógenos. Uma revisão siste...