6 documents found, page 1 of 1
In vivo study on the performance of therapeutic intraocular lens loaded with an...
Topete, Ana; Tang, Junmei; Lin, Quankui; Saramago, Benilde; Serro, Ana Paula
The effects of addition of functional monomers and molecular imprinting on dual...
Topete, Ana; Barahona, Isabel; Santos, Luís F.; Pinto, Carlos A.; Saraiva, Jorge A.; Serro, Ana Paula; Saramago, BenildeAlthough cataract surgery is considered a safe procedure, post-surgery complications such as endophthalmitis and ocular inflammation, may occur. To prevent this, antibiotics and anti-inflammatories are prescribed in the form of eye drops during the post-operatory period, but they lead to a low drug bioavailability in target tissues. The objective of this work is to develop an intraocular lens (IOL) material to ...
Dual drug delivery from hydrophobic and hydrophilic intraocular lenses: in-vitr...
Topete, Ana; Tang, Junmei; Ding, Xiaoxu; Filipe, Helena P; Saraiva, Jorge A.; Serro, Ana Paula; Lin, Quankui; Saramago, BenildePosterior capsule opacification (PCO) still remains the most frequent long term complication after cataract surgery, while endophthalmitis is rare but severe and should be prevented at all cost. Intraocular lenses (IOLs) with different designs (eg. edge and body-haptics angle) and materials (acrylic hydrophobic and acrylic hydrophilic surfaces) have been studied to reduce PCO. For the prevention of endophthalmi...
Controlled drug delivery from ophthalmic lenses
Topete, Ana; Oliveira, Andreia; Pimenta, Andreia; Silva, Diana; Carrilho, Magda; Paradiso, Patrizia; Kumar, Prashneel; Galante, Raquel; Mata, José
Effect of sterilization on drugs and lenses for ophthalmic applications
Topete, Ana; Oliveira, Andreia; Galante, Raquel; Bozukova, Dimitriya; Saramago, Benilde; Serro, A. P.
Effect of sterilization on chlorhexidine loaded soft contact lenses
Topete, Ana; Moutinho, Maria Guilhermina; Saramago, Benilde; Serro, Ana Paula