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Characterizing Human Cysticercosis In Portugal

Vilhena, M; Fonseca, AG; Marques, R; Dias, SS; Torgal, J

Abstract text Introduction: Cysticercosis results from the ingestion Taenia solium eggs directly by faecal-oral route or contaminated food or water. While, still considered a leading cause of acquired epilepsy in developed countries, this zoonosis has been controlled or eradicated in industrialized countries due to significant improvements in sanitation, pig rearing and slaughterhouse control systems. Objective...


Neurocysticercosis - The first documented clinical case in Mozambique

Santos, M.; Vilhena, M.; Prazeres, M.; Tsang, V.C.Tsang; Schantz, P.M.; Torgal, J

Neurocysticercosis is claimed to be endemic in some African countries. However no clinical case has been documented in Mozambique until now. We report the first clinical case of human neurocysticercosis in Mozambique, where we suspect that this disease is under-recognised.


Host- and microbe-related risk factors for and pathophysiology of fatal Rickett...

Sousa, R; França, A; Nóbrega, SD; Belo, A; Amaro, M; Abreu, T; Poças, J; Proença, P; Vaz, J; Torgal, J; Bacellar, F; Ismail, N; Walker, D

BACKGROUND: The pathophysiologic mechanisms that determine the severity of Mediterranean spotted fever (MSF) and the host-related and microbe-related risk factors for a fatal outcome are incompletely understood. METHODS: This prospective study used univariate and multivariate analyses to determine the risk factors for a fatal outcome for 140 patients with Rickettsia conorii infection admitted to 13 Portuguese h...


Intralesional expression of mRNA of interferon- gamma, tumor necrosis factor- a...

Sousa, R; Ismail, N; Nóbrega, SD; França, A; Amaro, M; Anes, M; Poças, J; Coelho, R; Torgal, J; Bacellar, F; Walker, D

BACKGROUND: The mechanisms of immunity to Rickettsia conorii that have been elucidated in mouse models have not been evaluated in human tissues. METHODS: In this study, quantitative real-time polymerase chain reaction was used to determine the levels of expression of inflammatory and immune mediators in skin-biopsy samples collected from 23 untreated patients with Mediterranean spotted fever (MSF). RESULTS: In ...



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