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Pathway to effective treatment for common mental and substance use disorders in...

Harris, Meredith G.; Kazdin, Alan E.; Hwang, Irving; Manoukian, Sophie M.; Sampson, Nancy A.; Stein, Dan J.; Viana, Maria Carmen; Vigo, Daniel V.

Funding Information: The US National Comorbidity Survey Replication (NCS-R) is supported by the National Institute of Mental Health (NIMH; U01-MH60220) with supplemental support from the National Institute of Drug Abuse (NIDA), the Substance Abuse and Mental Health Services Administration (SAMHSA), the Robert Wood Johnson Foundation (RWJF; Grant 044708), and the John W. Alden Trust. Funding Information: The Nor...


Obsessive-compulsive disorder in the World Mental Health surveys

Stein, Dan J.; Ruscio, Ayelet Meron; Altwaijri, Yasmin; Chiu, Wai Tat; Sampson, Nancy A.; Aguilar-Gaxiola, Sergio; Al-Hamzawi, Ali; Alonso, Jordi

Publisher Copyright: © 2025. The Author(s).; BACKGROUND: National surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and middle-income countries. Here we employ data from the World Mental Health surveys to characterize the onset, course, severity, and treatment of OCD acr...


Barriers to 12-month treatment of common anxiety, mood, and substance use disor...

Viana, Maria Carmen; Kazdin, Alan E.; Harris, Meredith G.; Stein, Dan J.; Vigo, Daniel V.; Hwang, Irving; Manoukian, Sophie M.; Sampson, Nancy A.

Funding Information: The World Mental Health Survey collaborators are Sergio Aguilar-Gaxiola, MD, PhD; Ali Al-Hamzawi, MD; Jordi Alonso, MD, PhD; Yasmin A. Altwaijri, PhD; Laura Helena Andrade, MD, PhD; Lukoye Atwoli, MD, PhD; Corina Benjet, PhD; Guilherme Borges, ScD; Evelyn J. Bromet, PhD; Ronny Bruffaerts, PhD; Brendan Bunting, PhD; Jose Miguel Caldas-de-Almeida, MD, PhD; Gra\u00E7a Cardoso, MD, PhD; Stephan...


Patterns and predictors of 12-month treatment of common anxiety, mood, and subs...

Stein, Dan J.; Vigo, Daniel V.; Harris, Meredith G.; Kazdin, Alan E.; Viana, Maria Carmen; Hwang, Irving; Kessler, Timothy L.; Manoukian, Sophie M.

Publisher Copyright: © The Author(s) 2025.; Background: Data from the World Mental Health (WMH) surveys on the coverage cascade has underscored the importance of perceived need for seeking treatment of mental disorders. However, little research has focused on treatment contact after adjusting for perceived need. We do so here in analysis of WMH data. Methods: The WMH data considered here come from 25 community ...


The case for eliminating excessive worry as a requirement for generalized anxie...

Ruscio, Ayelet Meron; Rassaby, Madeleine; Stein, Murray B.; Stein, Dan J.; Aguilar-Gaxiola, Sergio; Al-Hamzawi, Ali; Alonso, Jordi; Atwoli, Lukoye

Publisher Copyright: Copyright © The Author(s), 2024. Published by Cambridge University Press.; Background Around the world, people living in objectively difficult circumstances who experience symptoms of generalized anxiety disorder (GAD) do not qualify for a diagnosis because their worry is not 'excessive' relative to the context. We carried out the first large-scale, cross-national study to explore the impli...


Patterns, predictors, and patient-reported reasons for antidepressant discontin...

Kazdin, Alan E; Harris, Meredith G; Hwang, Irving; Sampson, Nancy A; Stein, Dan J; Viana, Maria Carmen; Vigo, Daniel V; Wu, Chi-Shin

The World Health Organization World Mental Health (WMH) Survey Initiative is supported by the United States National Institute of Mental Health (NIMH; R01 MH070884), the John D. and Catherine T. MacArthur Foundation, the Pfizer Foundation, the United States Public Health Service (R13-MH066849, R01-MH069864, and R01 DA016558), the Fogarty International Center (FIRCA R03-TW006481), the Pan American Health Organiz...


Findings from the World Mental Health Surveys of Civil Violence Exposure and It...

Axinn, William G.; Bruffaerts, Ronny; Kessler, Timothy L.; Frounfelker, Rochelle; Aguilar-Gaxiola, Sergio; Alonso, Jordi; Bunting, Brendan

Publisher Copyright: © 2023 American Medical Association. All rights reserved.; Importance: Understanding the association of civil violence with mental disorders is important for developing effective postconflict recovery policies. Objective: To estimate the association between exposure to civil violence and the subsequent onset and persistence of common mental disorders (in the Diagnostic and Statistical Manua...


Transdiagnostic development of internalizing psychopathology throughout the lif...

De Vries, Ymkje Anna; Al-Hamzawi, Ali; Alonso, Jordi; Andrade, Laura Helena; Benjet, Corina; Bruffaerts, Ronny; Bunting, Brendan; De Girolamo, Giovanni

Funding: The Portuguese Mental Health Study was carried out by the Department of Mental Health, Faculty of Medical Sciences, NOVA University of Lisbon, with collaboration of the Portuguese Catholic University, and was funded by Champalimaud Foundation, Gulbenkian Foundation, Foundation for Science and Technology (FCT) and Ministry of Health; Background Depressive and anxiety disorders are highly comorbid, which...


Increased risks for mental disorders among LGB individuals

Gmelin, Jan Ole H.; De Vries, Ymkje Anna; Baams, Laura; Aguilar-Gaxiola, Sergio; Alonso, Jordi; Borges, Guilherme; Bunting, Brendan; Cardoso, Graca

Funding Information: The World Health Organization World Mental Health (WMH) Survey Initiative is supported by the United States National Institute of Mental Health (NIMH; R01 MH070884), the John D. and Catherine T. MacArthur Foundation, the Pfizer Foundation, the United States Public Health Service (R13-MH066849, R01-MH069864, and R01 DA016558), the Fogarty International Center (FIRCA R03-TW006481), the Pan Am...


Previous disorders and depression outcomes in individuals with 12-month major d...

Roest, Annelieke M.; De Vries, Ymkje Anna; Al-Hamzawi, Ali; Alonso, Jordi; Ayinde, Olatunde O.; Bruffaerts, Ronny; Bunting, Brendan

Funding Information: The World Health Organization World Mental Health (WMH) Survey Initiative is supported by the United States National Institute of Mental Health (NIMH; R01 MH070884), the John D. and Catherine T. MacArthur Foundation, the Pfizer Foundation, the United States Public Health Service (R13-MH066849, R01-MH069864 and R01 DA016558), the Fogarty International Center (FIRCA R03-TW006481), the Pan Ame...


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