O lenvatinib é um fármaco usado em doentes com carcinoma hepatocelular (CHC) irressecável, devido à sua atividade antiangiogénica. Esta classe de fármacos mudou o paradigma do tratamento do CHC mas apresenta agora um desafio adicional devido aos efeitos secundários significativamente diferentes comparativamente à quimioterapia convencional. Apresentamos o caso de um homem de 58 anos com cirrose alcoólica e dism...
Introduction: Transformational leadership in nursing has the potential to enhance nurses' performance in hospital settings, fostering quality of care, job satisfaction and organisational commitment. Objectives: To map the existing evidence regarding the influence of TL on nurses' performance in hospital contexts. Methodology: A scoping review was conducted according to the Joanna Briggs Institute methodology an...
In this paper we present CoR a resource oriented computing model that address the question of how to integrate user-level fine-grained multithreading, communication and coordination into a cluster of symmetrical multiprocessor computers. To support the design of complex distributed application using the proposed paradigm we built pCoR a run-time system which has new areas that represents extensions to the stric...
In this paper we concentrate in the efforts made to exploit the performance of Myrinet to build a faster communication route into CoR1. By accessing the Myrinet interface through GM2, we achieved low latency and high bandwidth message passing without the overhead of a higher level protocol stack, system calls or interrupts. CoR is an ongoing project unique in its design goal of combining multithreading, message...