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Maternal dietary exposure to mycotoxin aflatoxin B1 promotes intestinal immune ...

Bastos-Amador, Patricia; Duarte, Elsa Leclerc; Torres, Júlio; Caldeira, Ana Teresa; Silva, Inês; Salvador, Cátia; Assunção, Ricardo; Alvito, Paula

Abstract: Mycotoxins are secondary metabolites produced by fungi occurring in food that are toxic to animals and humans. Early-life mycotoxins exposure has been linked to diverse pathologies. However, how maternal exposure to mycotoxins impacts on the intestinal barrier function of progeny has not been explored. Here, exposure of pregnant and lactating C57Bl/6J female mice to aflatoxin B1 (AFB1; 400 μg/kg body ...


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