RESUMO: O manual escolar é um recurso didático muito utilizado em contexto escolar. Deste modo, a qualidade deste recurso é crucial devendo ser elaborado de forma correta, completa e diversificada. O objetivo deste estudo é avaliar o questionamento do subtema “Estrutura e dinâmica interna da Terra” presente nos manuais do 7.º ano de escolaridade da disciplina de Ciências Naturais. Para esta análise, utilizaram-...
The perturbation of the symbiotic relationship between microbes and intestinal immune system contributes to gut inflammation and Inflammatory Bowel Disease (IBD) development. The host mucosa glycans (glycocalyx) creates a major biological interface between gut microorganisms and host immunity that remains ill-defined. Glycans are essential players in IBD immunopathogenesis, even years before disease onset. Howe...
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease often associated with underlying inflammatory bowel disease (IBD). This study investigates how PSC predisposes individuals to altered inflammatory immune responses compared with IBD alone. A case–control study was conducted with a cohort of 75 patients, including 16 with PSC (14 with concomitant IBD), 39 with IBD alone, and 20 controls....
Despite the growing body of research suggesting the benefits of integrating comics into teaching practices, research on teachers' attitudes towards using comics in education is scarce. The aim of this study was to examine comic book reading habits and attitudes of preservice elementary teachers regarding the use of comics in education. The results revealed a lack of comic book reading habits: 37% indicated they...
The aim of this pilot study was to understand how the use of science comics, centred on complex scientific knowledge, can promote students’ engagement with science, in order to discuss its potentialities as a tool to communicate science for the general public. The qualitative study involved 175 students and 7 teachers. The results revealed that the use of comics significantly increases students’ motivation and ...
Background and aims: Durable clinical remission, endoscopic healing, and biomarker normalization are key treatment goals for Crohn's disease. The selective anti-interleukin-23 p19 inhibitor risankizumab has demonstrated efficacy and safety in moderately to severely active Crohn's disease. This post-hoc analysis of data from the pivotal risankizumab maintenance study assessed whether risankizumab maintenance the...
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract that might lead to progressive bowel damage and disability. The exact cause of Crohn's disease is unknown, but evidence points towards multifactorial events causing dysregulation of the innate immune system in genetically susceptible people. Commonly affecting the terminal ileum and proximal colon, Crohn's disease inflammation is of...
Purpose of review: Inflammatory Bowel Disease (IBD) is a chronic GI inflammatory condition induced by a dysregulated immune system activation, whereas HIV infection causes depletion of the immune system, inducing immunosuppression. Given the increasing incidence of IBD across the globe, including in developing countries, the co-prevalence of both conditions is expected to increase. Herein, we systematically rev...
The aim of this pilot study was to understand how the use of science comics can promote students’ engagement with science, in order to discuss its potentialities as a tool to communicate science for the general public, even when involves more complex scientific knowledge. The qualitative study involved 175 students and 7 teachers. The results revealed that the use of comics significantly increases students’ mot...
Establishing and nurturing strong patient relations stands as an essential pillar in the framework of UEG. Within Europe's diverse healthcare landscape, fostering strong relations and collaboration among the digestive health community will not only optimize healthcare outcomes but also establish solidarity and mutual understanding between healthcare professionals, patients, and patient advocates. By prioritizin...