3 documents found, page 1 of 1
Atividade biológica de extratos orgânicos e aquosos de macroalgas marinhas do E...
Torres, Márcia Rocha; Sousa, Alessandra de Paula Alves; Silva Filho, Eduardo Augusto Torres da; Pessoa, Cláudia; Moraes, Maria Elisabete Amaral deThe present study evaluated the biological activity of 12 marine macroalgae from Ceará State, Brazil. From the collected species 48 extracts (aqueous, dichloromethane, acetone and methanol extracts for each species) were obtained. The activity of extracts were rated at the following bioactivities: lethality in brine shrimp nauplii, inhibition of the development of sea urchin eggs, hemolytic activity on mice ery...
The renal effects of alginates isolated from brown seaweed Sargassum vulgare
Sousa, Alessandra de Paula Alves ,; Barbosa, Paulo Sergio Ferreira; Torres, Márcia Rocha; Martins, Alice Maria Costa; Martins, René DuarteAlginates isolated from Sargassum vulgare , present a strong antitumor activity, associated with kidney reversible damage, as analysed by histopathology of treated animals. In the present study, the renal alteration mechanisms of S. vulgare alginates were investigated using the isolated perfused rat kidney and the isolated perfused rat mesenteric blood vessel methods. The results showed that the effects of Sarg...
In vivo growth-inhibition of Sarc oma 180 tumor by alginates from brown seaweed...
Sousa, Alessandra Paula Alves de; Torres, Márcia Rocha; Pessoa, Cláudia; Moraes Filho, Manoel Odorico de; Rocha Filho, Francisco DárioPrevious studies had demonstrated that alginates from Sargassum sp. (Phaeophyta) showed a considerable activity against various murine tumors. The aim present study is to investigate the in vivo antitumor activity of two alginates (SVHV and SVLV) with di V erent viscosity extracted from brown seaweed Sargassum vulgare C. Agardh against Sarcoma 180 cells transplanted in mice. Both alginates inhibited growth of s...