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Impaired skin barrier is one of the hallmarks of atopic dermatitis (AD), with abnormalities in the cornified envelope, lipid lamellae, tight junctions and cutaneous microbiome. These findings are also present in nonlesional skin of AD individuals, suggesting that epidermal barrier defects may be the initial step towards the development of AD and eventually other atopic diseases (atopic march). It is currently k...
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Introduction: Acute bacterial dermo-hypodermatitis (DHAB) is an acute infection of the dermis and hypodermis that most often affects the lower limbs. Although diabetes mellitus has been identified as a risk factor for its development, recent studies have questioned this relationship. The aim of the present study was to compare clinical characteristics of inpatients with DHAB associated or not with diabetes mell...