10 documents found, page 1 of 1
Projecting Ancient Ancestry in Modern-Day Arabians and Iranians: A Key Role of ...
Ferreira, JC; Alshamali, F; Montinaro, F; Cavadas, B; Torroni, A; Pereira, L; Raveane, A; Fernandes, VThe Arabian Peninsula is strategic for investigations centered on the early structuring of modern humans in the wake of the out-of-Africa migration. Despite its poor climatic conditions for the recovery of ancient human DNA evidence, the availability of both genomic data from neighboring ancient specimens and informative statistical tools allow modeling the ancestry of local modern populations. We applied this ...
The mitogenome portrait of Umbria in Central Italy as depicted by contemporary ...
Modi, A; Lancioni, H; Cardinali, I; Capodiferro, MR; Rambaldi Migliore, N; Hussein, A; Strobl, C; Bodner, M; Schnaller, L; Xavier, C; Rizzi, EUmbria is located in Central Italy and took the name from its ancient inhabitants, the Umbri, whose origins are still debated. Here, we investigated the mitochondrial DNA (mtDNA) variation of 545 present-day Umbrians (with 198 entire mitogenomes) and 28 pre-Roman individuals (obtaining 19 ancient mtDNAs) excavated from the necropolis of Plestia. We found a rather homogeneous distribution of western Eurasian lin...
Population structure of modern-day Italians reveals patterns of ancient and arc...
Raveane, A; Aneli, S; Montinaro, F; Athanasiadis, G; Barlera, S; Birolo, G; Boncoraglio, G; Di, Blasio, AM; Di, Gaetano, C; Pagani, L; Parolo, SEuropean populations display low genetic differentiation as the result of long-term blending of their ancient founding ancestries. However, it is unclear how the combination of ancient ancestries related to early foragers, Neolithic farmers, and Bronze Age nomadic pastoralists can explain the distribution of genetic variation across Europe. Populations in natural crossroads like the Italian peninsula are expect...
Reconciling evidence from ancient and contemporary genomes: a major source for ...
Pereira, JB; Costa, MD; Vieira, D; Pala, M; Bamford, L; Harich, N; Cherni, L; Alshamali, F; Hatina, J; Rychkov, S; Stefanescu, G; King, T; Torroni, AImportant gaps remain in our understanding of the spread of farming into Europe, due partly to apparent contradictions between studies of contemporary genetic variation and ancient DNA. It seems clear that farming was introduced into central, northern, and eastern Europe from the south by pioneer colonization. It is often argued that these dispersals originated in the Near East, where the potential source genet...
Origin and spread of mitochondrial DNA haplogroup U7
Sahakyan, H; Kashani, BH; Tamang, R; Kushniarevich, A; Francis, A; Costa, MD; Pathak, AK; Khachatryan, Z; Sharma, I; van Oven, M; Parik, JHuman mitochondrial DNA haplogroup U is among the initial maternal founders in Southwest Asia and Europe and one that best indicates matrilineal genetic continuity between late Pleistocene huntergatherer groups and present-day populations of Europe. While most haplogroup U subclades are older than 30 thousand years, the comparatively recent coalescence time of the extant variation of haplogroup U7 (~16–19 thous...
Mitochondrial DNA signals of Late Glacial recolonization of Europe from Near Ea...
Pala, M; Olivieri, A; Achilli, A; Accetturo, M; Metspalu, E; Reidla, M; Tamm, E; Karmin, M; Reisberg, T; Hooshiar Kashani, B; Perego, UA; Carossa, VHuman populations, along with those of many other species, are thought to have contracted into a number of refuge areas at the height of the last Ice Age. European populations are believed to be, to a large extent, the descendants of the inhabitants of these refugia, and some extant mtDNA lineages can be traced to refugia in Franco-Cantabria (haplogroups H1, H3, V, and U5b1), the Italian Peninsula (U5b3), and t...
Mitochondrial genomes from modern horses reveal the major haplogroups that unde...
Achilli, A; Olivieri, A; Soares, P; Lancioni, H; Kashani, BH; Perego, UA; Nergadze, SG; Carossa, V; Santagostino, M; Capomaccio, S; Felicetti, MArchaeological and genetic evidence concerning the time and mode of wild horse (Equus ferus) domestication is still debated. High levels of genetic diversity in horse mtDNA have been detected when analyzing the control region; recurrent mutations, however, tend to blur the structure of the phylogenetic tree. Here, we brought the horse mtDNA phylogeny to the highest level of molecular resolution by analyzing 83 ...
The Matrilineal Ancestry of Ashkenazi Jewry: Portrait of a Recent Founder Event
Behar, DM; Metspalu, E; Kivisild, T; Achilli, A; Hadid, Y; Tzur, S; Pereira, L; Amorim, A; Quintana-Murci, L; Majamaa, K; Herrnstadt, C; Howell, NBoth the extent and location of the maternal ancestral deme from which the Ashkenazi Jewry arose remain obscure. Here, using complete sequences of the maternally inherited mitochondrial DNA (mtDNA), we show that close to one-half of Ashkenazi Jews, estimated at 8,000,000 people, can be traced back to only 4 women carrying distinct mtDNAs that are virtually absent in other populations, with the important excepti...
Phylogeography of the human mitochondrial haplogroup L3e: a snapshot of African...
Bandelt, H-J; Alves-Silva, J; Guimarães, PEM; Santos, MS; Brehm, A; Pereira, L; Coppa, A; Larruga, JM; Rengo, C; Scozzari, R; Torroni, A; Prata, MJThe mtDNA haplogroup L3e, which is identified by the restriction site +2349 MboI within the Afro-Eurasian superhaplogroup L3 (-3592 HpaI), is omnipresent in Africa but virtually absent in Eurasia (except for neighbouring areas with limited genetic exchange). L3e was hitherto poorly characterised in terms of HVS-I motifs, as the ancestral HVS-I type of L3e cannot be distinguished from the putative HVS-I ancestor...
Prehistoric and historic traces in the mtDNA of Mozambique: insights into the B...
Pereira, L; Macaulay, V; Torroni, A; Scozzari, R; Prata, MJ; Amorim, AA sample of mitochondrial DNA (mtDNA) from the southeastern African population of Mozambique has been shown to have affinities with populations both to its north and south. From the north came sequences that may have been involved in the Bantu expansion (from western, through eastern, to southern Africa), such as members of haplogroups L3b, L3e1a and a subset of L1a. The dating of the major component of Mozambi...