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Safety, Efficacy and Pharmacokinetics of daily optimised doses of Rifampicin fo...
Espinosa-Pereiro, J; Aguiar, A; Nara, E; Medina, A; Molinas, G; Tavares, M; Tortola, T; Ghimire, S; Alfenaar, JC; Sturkenboom, MGG; Magis-Escurra, C"Background: Higher than standard doses of rifampicin could improve the treatment outcome of drug-susceptible tuberculosis without compromising the safety of patients. Methods: We performed a systematic review of prospective clinical studies including adults with pulmonary and extrapulmonary TB receiving rifampicin doses above 10mg/kg/day. We extracted the data on overall adverse events (AE), hepatic AE, sputum...
Date: 2025
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Origin: Repositório Aberto da Universidade do Porto