24 documents found, page 1 of 3
Distribution of Chlamydia trachomatis ompA-genotypes over three decades in Port...
Lodhia, Zohra; Cordeiro, Dora; Correia, Cristina; João, Inês; Carreira, Teresa; Vieira, Luís; Nunes, Alexandra; Ferreira, Rita; Schäfer, SandraObjectives: Chlamydia trachomatis is classified into 15 major genotypes, A to L3, based on the diversity of ompA gene. Here, we evaluated and characterised the distribution and diversity of ompA-genotypes over 32 years (1990–2021) in Portugal. Methods: The collection of the Portuguese National Reference Laboratory for Sexually Transmitted Infections includes 5824 C. trachomatis-positive samples that were succes...
Short and Long-Term Trajectories of the Post COVID-19 Condition: Results From t...
Santoro, Andrea; Bai, Francesca; Greco, Maria Francesca; Rovito, Roberta; Sala, Matteo; Borghi, Lidia; Piscopo, Kyrie; Vegni, ElenaBackground: Post COVID-19 condition (PCC) affects 10-40% of patients and is characterized by persisting symptoms at ≥ 4 weeks after SARS-CoV-2 infection. Symptoms can last 7 or even more months. How long PCC persists and any changes in its clinical phenotypes over time require further investigation. We investigated PCC trajectories and factors associated with PCC persistence. Material and methods: We included b...
Comparison of Multi-locus Genotypes Detected in Aspergillus fumigatus Isolated ...
Morais, Susana; Toscano, Cristina; Simões, Helena; Carpinteiro, Dina; Viegas, Carla; Veríssimo, Cristina; Sabino, RaquelBackground: Aspergillus fumigatus is a saprophytic fungus, ubiquitous in the environment and responsible for causing infections, some of them severe invasive infections. The high morbidity and mortality, together with the increasing burden of triazole-resistant isolates and the emergence of new risk groups, namely COVID-19 patients, have raised a crescent awareness of the need to better comprehend the dynamics ...
Comparison of multi-locus genotypes detected in Aspergillus fumigatus isolated ...
Morais, Susana; Toscano, Cristina; Simões, Helena; Carpinteiro, Dina; Viegas, Carla; Veríssimo, Cristina; Sabino, RaquelBackground: Aspergillus fumigatus is a saprophytic fungus, ubiquitous in the environment, and responsible for causing infections, some of them severe invasive infections. The high morbidity and mortality, together with the increasing burden of triazole-resistant isolates and the emergence of new risk groups, namely COVID-19 patients, have raised a crescent awareness of the need to better comprehend the dynamics...
Invasive and Subcutaneous Infections Caused by Filamentous Fungi: Report from a...
Veríssimo, Cristina; Toscano, Cristina; Ferreira, Teresa; Abreu, Gabriela; Simões, Helena; Diogo, José; Carvalho, Dinah; Santiago, Felicidade; Lima, AnaInvasive fungal infections (IFI) have significantly increased over the past years due to advances in medical care for the at-risk immunocompromised population. IFI are often difficult to diagnose and manage, and can be associated with substantial morbidity and mortality. This study aims to contribute to understanding the etiology of invasive and subcutaneous fungal infections, their associated risk factors, and...
Multilocus genotyping of Aspergillus fumigatus isolated from patients diagnosed...
Morais, Susana; Toscano, Cristina; Simões, Helena; Carpinteiro, Dina; Viegas, Carla; Verissímo, Cristina; Sabino, RaquelAspergillus fumigatus is an environmental fungus responsible for causing severe invasive infections, especially in immunocompromised individuals. In 2020, during SARS-CoV-2 pandemics, a high number of cases of pulmonary aspergillosis was detected in COVID-19 patients, leading to the definition of CAPA (COVID-19 associated pulmonary aspergillosis). Patients with CAPA harbor many baseline prognostic factors with ...
Transcontinental dissemination of the L2b/D-Da recombinant Chlamydia trachomati...
Borges, Vítor; Isidro, Joana; Correia, Cristina; Cordeiro, Dora; Vieira, Luís; Lodhia, Zohra; Fernandes, Cândida; Rodrigues, Ana Maria; Azevedo, JacintaPreviously, we identified a Chlamydia trachomatis Lymphogranuloma venereum (LGV) recombinant strain possessing a unique non-LGV ompA genotype. Here, culture-independent genome sequencing confirms its circulation in Europe, Middle East and North America, and unveils genetic evidence of emergence of antibiotic resistance. Multi-country and systematic molecular surveillance is needed.
COVID-19-Associated Invasive Pulmonary Aspergillosis in the Intensive Care Unit...
Ranhel, David; Ribeiro, Ana; Batista, Judite; Pessanha, Maria; Cristovam, Elisabete; Duarte, Ana; Dias, Ana; Coelho, Luís; Monteiro, FilipaInvasive pulmonary aspergillosis (IPA) has become a recognizable complication in coronavirus disease 2019 (COVID-19) patients admitted to intensive care units (ICUs). Alveolar damage in the context of acute respiratory distress syndrome (ARDS) appears to be the culprit in facilitating fungal invasion in COVID-19 patients, leading to a COVID-19-associated pulmonary aspergillosis (CAPA) phenomenon. From November ...
Transcontinental Dissemination of the L2b/D-Da Recombinant Chlamydia trachomati...
Borges, Vítor; Isidro, Joana; Correia, Cristina; Cordeiro, Dora; Vieira, Luís; Lodhia, Zohra; Fernandes, Cândida; Rodrigues, Ana Maria; Azevedo, JacintaPreviously, we identified a Chlamydia trachomatis lymphogranuloma venereum (LGV) recombinant strain possessing a non-LGV ompA genotype. Here, culture-independent genome sequencing confirms its circulation in Europe, Middle East, and North America, and unveils emergence of antibiotic resistance. Broad surveillance is needed.
Trends on Aspergillus epidemiology: perspectives from a national reference labo...
Sabino, Raquel; Gonçalves, Paulo; Martins-Melo, Aryse; Simões, Daniela; Oliveira, Mariana; Francisco, Mariana; Viegas, Carla; Carvalho, DinahIdentification of Aspergillus to species level is important since sibling species may display variable susceptibilities to multiple antifungal drugs and also because correct identification contributes to improving the knowledge of epidemiological studies. Two retrospective laboratory studies were conducted on Aspergillus surveillance at the Portuguese National Mycology Reference Laboratory. The first, covering ...