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From trihalomethanes chronic daily intake through multiple exposure routes to c...

Costa, C; Assunção, R; Sequeira, D; Esteves, F; Valdiglesias, V; Laffon, B; Teixeira, JP; Madureira, J

This study aimed to estimate chronic daily intake (CDI) and to predict the attributable lifetime cancer risk (LCR) and hazard index (HI) from concurrent exposure to four trihalomethanes (THMs; chloroform, bromodichloromethane, dibromochloromethane and bromoform), via multiple exposure routes (oral ingestion, dermal contact and inhalation), among 238 non-competitive attendees of 10 Portuguese public indoor swimm...


Are Data from Mycotoxins' Urinary Biomarkers and Food Surveys Linked? A Review ...

Martins, C; Assunção, R; Nunes, C; Torres, Duarte; Alvito, P

Mycotoxins are natural chemical contaminants of foods, posing several health risks to humans. Biomarkers-driven research has been used as a tool for a more accurate characterization of the internal exposure. Whether certain food items are predictors of exposure to mycotoxins constitutes an important aspect for the risk assessment of mycotoxins. Comprehensive human biomonitoring studies linked with food surveys ...


Risk-benefit assessment of cereal-based foods consumed by portuguese children a...

Assunção, R; Boué, G; Alvito, P; Brazão, R; Carmona, P; Carvalho, C; Correia, D; Fernandes, P; Lopes, C; Martins, C; Membré, JM; Monteiro, S; Nabais, P

Cereal-based foods, including breakfast (BC) and infant cereals (IC), are among the first solid foods introduced to infants. BC and IC are sources of macro and micronutrients that have bene-ficial effects on health, but can also be sources of harmful chemical and microbiological contaminants and nutrients that may lead to adverse health effects at high consumption levels. This study was performed under the Risk...


Dietary exposure to Cadmium and the associated burden – results from a duplicat...

Sousa, Ana; Assunção, R; Coelho, S; Kunisue, T; Tanabe, S; Pastorinho, M. Ramiro

Cadmium is a toxic metal classified as human carcinogen (Group 1) and considered an endocrine disruptor. Human exposure in the non-smoking general population occurs mainly via food ingestion. In order to evaluate the levels of Cd exposure trough food intake in Portugal and the associated burden, a duplicate diet study was conducted in the city of Aveiro, Portugal, in 2012.


Food Consumption Data as a Tool to Estimate Exposure to Mycoestrogens

Martins, C; Torres, D; Lopes, C; Correia, D; Goios, AC; Assunção, R; Alvito, P; Vidal, A; de Boevre, M; de Saeger, S; Nunes, C

Zearalenone and alternariol are mycotoxins produced by Fusarium and Alternaria species, respectively, that present estrogenic activity and consequently are classified as endocrine disruptors. To estimate the exposure of the Portuguese population to these two mycotoxins at a national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering as inputs: i) the food consump...


Exposure assessment of Portuguese population to multiple mycotoxins: the human ...

Martins, Carla; Vidal, A.; De Boevre, M.; De Saeger, S.; Nunes, C.; Torres, D.; Goios, A.; Lopes, C.; Assunção, R; Alvito, P.

Mycotoxins constitute a relevant group of food contaminants with several associated health outcomes such as estrogenic, immunotoxic, nephrotoxic and teratogenic effects. Although scarce data are available in Portugal, human biomonitoring studies have been globally developed to assess the exposure to mycotoxins at individual level. In order to overcome this lack of data, the present study concerned the analysis ...


Burden of disease attributable to exposure to aflatoxins in Portugal using Huma...

Martins, C; Vidal, A; De Boevre, M; De Saeger, S; Nunes, C; Torres, Duarte; Goios, A; Lopes, C; Alvito, P; Assunção, R

<jats:title>Abstract</jats:title> <jats:sec> <jats:title /> <jats:p>Human biomonitoring (HBM) is recognized as an important tool to assess the Human exposure to chemicals, contributing to describe trends and patterns of exposure over time and to identify population groups that could be under risk. Natural chemicals as mycotoxins, fungi metabolites that produce toxic effects in humans, are important compounds th...


Exposure assessment of Portuguese population to multiple mycotoxins: The human ...

Martins, C; Vidal, A; De Boevre, M; De Saeger, S; Nunes, C; Torres, Duarte; Goios, A; Lopes, C; Assunção, R; Alvito, P

Mycotoxins constitute a relevant group of food contaminants with several associated health outcomes such as estrogenic, immunotoxic, nephrotoxic and teratogenic effects. Although scarce data are available in Portugal, human biomonitoring studies have been globally developed to assess the exposure to mycotoxins at individual level. In order to overcome this lack of data, the present study concerned the analysis ...


Risk assessment of Portuguese population to multiple mycotoxins: the human biom...

Martins, C; Vidal, A; De Saeger, S; Nunes, C; Torres, Duarte; Goios, A; Lopes, C; Assunção, R; Alvito, P; De Boevre, M

<jats:title>Abstract</jats:title> <jats:sec> <jats:title /> <jats:p>Mycotoxins constitute a relevant group of food contaminants with several associated health outcomes such as estrogenic, immunotoxic, nephrotoxic and teratogenic effects. Although scarce data are available in Portugal, human biomonitoring studies have been globally developed to assess the exposure to mycotoxins at individual level.</jats:p> <jat...


Exposure of Portuguese population to mycotoxins: the contribution of human biom...

Martins, C; De Boevre, M; De Saeger, S; Assunção, R; Nunes, C; Torres, Duarte; Goios, A; Lopes, C; Alvito, P; Vidal, A


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