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Impact of the COVID-19 pandemic on antidepressant consumption in the Central re...

Negrao, LG; Coelho, C; Castel-Branco, MM; Figueiredo, IV; Fernandez-Llimos, F

PurposeTo evaluate the impact of the pandemic on the consumption of antidepressive agents in Central Portugal.MethodsTo estimate the causal effect of the pandemic an interrupted time series analysis was conducted. Data of antidepressant drugs monthly dispensed in community pharmacies between Jan-2010 and Dec-2021 were provided by the regional Health Administration. Anti-Parkinson dopaminergic agents and statins...



Influence of automated indexing in Medical Subject Headings (MeSH) selection fo...

Fernandez-Llimos, F; Negrao, LG; Bond, C; Stewart, D

Background: The Medical Subject Headings (MeSH) thesaurus is the controlled vocabulary used to index articles in MEDLINE. MeSH were mainly manually selected until June 2022 when an automated algorithm, the Medical Text Indexer (MTI) automated was fully implemented. A selection of automated indexed articles is then reviewed (curated) by human indexers to ensure the quality of the process. Objective: To describe ...


Evaluation of Medical Subject Headings assignment in simulated patient articles

Tonin, FS; Negrao, LG; Meza, IP; Fernandez Llimos, F

Objectives To evaluate human-based Medical Subject Headings (MeSH) allocation in articles about 'patient simulation'-a technique that mimics real-life patient scenarios with controlled patient responses.Methods A validation set of articles indexed before the Medical Text Indexer-Auto implementation (in 2019) was created with 150 combinations potentially referring to 'patient simulation'. Articles were classifie...


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