8 documents found, page 1 of 1
A catalytically inactive Lys49 PLA2 isoform from Bothrops jararacussu venom tha...
Fagundes, Fabio H. R. [UNESP]; Aparício, Ricardo; Dos Santos, Marcelo L.; Filho, Eduardo B. S. Diz [UNESP]; Oliveira, Simone C. B. [UNESP]Made available in DSpace on 2022-04-29T00:50:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-11-01; A new secretory phospholipase A2 (sPLA2) isoform from Bothrops jararacussu venom (BjVIII) has been characterized by causing platelet aggregation, an absent activity in BthTx-I, Prtx-I and PrTx-II sPLA2s. According to our results, BjVIII also enhances insulin release by the pancreatic beta cells. The com...
Non-clinical studies for evaluation of 8-C-rhamnosyl apigenin purified from pep...
Tamayose, Cinthia I.; Romoff, Paulete; Toyama, Daniela O.; Gaeta, Henrique H. [UNESP]; Costa, Caroline R. C. [UNESP]; Belchor, Mariana N. [UNESP]Made available in DSpace on 2018-12-11T17:14:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-09-14; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Compound 8-C-rhamnosyl apigenin (8CR) induced a moderate reduction in the enzymatic activity of secretory phospholipase A2 (sPLA2) from Crotalus durissus terrificus and cy...
Harpalycin 2 inhibits the enzymatic and platelet aggregation activities of PrTX...
Ximenes, Rafael M.; Alves, Renata S.; Pereira, Ticiana P.; Araujo, Renata M.; Silveira, Edilberto R.; Rabello, Marcelo M.; Hernandes, Marcelo Z.Made available in DSpace on 2013-08-28T14:14:23Z (GMT). No. of bitstreams: 1 WOS000312325000001.pdf: 1687045 bytes, checksum: 81c838bb86f5cc0e9eecf68046ea6082 (MD5); Made available in DSpace on 2013-09-30T17:41:27Z (GMT). No. of bitstreams: 2 WOS000312325000001.pdf: 1687045 bytes, checksum: 81c838bb86f5cc0e9eecf68046ea6082 (MD5) WOS000312325000001.pdf.txt: 42001 bytes, checksum: b4a008ad203891063588dc25c979630f...
Isolation, homology modeling and renal effects of a C-type natriuretic peptide ...
Alves, Renata S.; Ximenes, Rafael M.; Jorge, Antonio R.C.; Nascimento, Nilberto R.F.; Martins, René D.; Rabello, Marcelo M.; Hernandes, Marcelo Z.Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:30:52Z No. of bitstreams: 0; Made available in DSpace on 2014-05-27T11:30:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-11-01; Mammalian natriuretic peptides (NPs) have been extensively investigated for use as therapeutic agents in the treatment of cardiovascular diseases. Here, we describe the isolation, sequ...
Modulation of the pharmacological effects of enzymatically-active PLA 2 by BTL-...
Oliveira, Simone C.B.; Fonseca, Fabiana V.; Antunes, Edson; Camargo, Enilton A.; Morganti, Rafael P.; Aparício, Ricardo; Toyama, Daniela O.Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:23:36Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:40:47Z : No. of bitstreams: 1 2-s2.0-46649109942.pdf: 446690 bytes, checksum: 87558c09dd78812dbd892f265a25a877 (MD5); Made available in DSpace on 2014-05-27T11:23:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-07-11; Background. An interaction between ...
Modulation of the Pharmacological Activities of Secretory Phospholipase A2 from...
Santos, Marcelo L.; Toyama, Daniela O.; Oliveira, Simone C. B.; Cotrim, Camila A.; Diz-Filho, Eduardo B. S.; Fagundes, Fabio H. R.Made available in DSpace on 2013-08-28T14:10:40Z (GMT). No. of bitstreams: 1 WOS000286596400053.pdf: 814045 bytes, checksum: bc5e8a1bab23314167aefae0d76e7ae9 (MD5); Made available in DSpace on 2013-09-30T19:22:38Z (GMT). No. of bitstreams: 2 WOS000286596400053.pdf: 814045 bytes, checksum: bc5e8a1bab23314167aefae0d76e7ae9 (MD5) WOS000286596400053.pdf.txt: 64546 bytes, checksum: e5963418daf997124dc66df5387222fb (...
Vasoconstrictor effect of Africanized honeybee (Apis mellifera L.) venom on rat...
Sousa, Paulo Cesar P.; Brito, Teresinha S.; Freire, Daniel S.; Ximenes, Rafael M.; Magalhaes, Pedro Jorge C.; Monteiro, Helena S. A.; Alves, Renata S.Made available in DSpace on 2014-12-03T13:11:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-09-25Bitstream added on 2014-12-03T13:23:33Z : No. of bitstreams: 1 WOS000325247700002.pdf: 661869 bytes, checksum: 1ee9f647378be469eba77b99b039d342 (MD5); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Cearense Foundat...
Vasoconstrictor effect of Africanized honeybee (Apis mellifera L.) venom on rat...
Sousa, Paulo César P.; Brito, Teresinha S.; Freire, Daniel S.; Ximenes, Rafael M.; Magalhães, Pedro Jorge C.; Monteiro, Helena S. A.Background: Apis mellifera stings are a problem for public health worldwide, particularly in Latin America due to the aggressiveness of its Africanized honeybees. Massive poisoning by A. mellifera venom (AmV) affects mainly the cardiovascular system, and several works have described its actions on heart muscle. Nevertheless, no work on the pharmacological action mechanisms of the AmV in isolated aorta has been ...