Mutations linked to neurodevelopmental disorders, such as intellectual disability (ID), are frequently found in genes that encode for proteins of the excitatory synapse. Transmembrane AMPA receptor regulatory proteins (TARPs) are AMPA receptor auxiliary proteins that regulate crucial aspects of receptor function. Here, we investigate a mutant form of the TARP family member stargazin, described in an ID patient....
Por todo mundo, um crescente número de instituições de ensino superior vem desenvolvendo programas de pacientes padronizados. Comuns na formação pré-graduada em medicina e enfermagem, começam-se a encontrar noutras profissões de saúde. A inexistência de precedentes em instituições similares em Portugal estabelece a necessidade de criar de raiz um programa ajustado à realidade da ESS|P.PORTO. O propósito do pres...
This study aimed to test whether the Behavioral Regulation in Sport Questionnaire and the Behavioral Regulation in Exercise Questionnaire can measure the same constructs in an equivalent manner. Advanced statistical procedures were used to examine if these scales could be interchangeably applied to the sport and the exercise context. In total, 2256 individuals (athletes = 1099; exercisers = 1157) completed tran...
This study analyzed independent and codependent effects of task- and ego-involving motivational climates on basic psychological need satisfaction and behavioral regulation (i.e., autonomous and controlled motivation) among young athletes. Participants were young Portuguese female (n = 114) and male (n = 324) swimmers, nested within four different clubs. Participants completed a multisection survey, assessing mo...
Purpose: To date, most research on the assessment of motivation has been exerciser-focused and has not considered how fitness professionals' motivations impact their behaviors toward exercisers during training sessions. The purpose of this study was to examine the factor structure of the Coach Motivation Questionnaire in a sample of fitness professionals (CMQ-FP) to ascertain its usefulness for this vocational ...
Extract: In 2017, the notification rate of tuberculosis in the Northern Region of Portugal was 21.1 cases per 100 000 inhabitants. According to the National Tuberculosis Programme Surveillance System (SVIG-TB), poly-resistance to isoniazid and streptomycin (PR-HS) represented 2.6–5% of the cases notified in the Northern Region between 2009 and 2017 Although they represent a relatively low proportion of cases in...
Purpose: To date, most research on the assessment of motivation has been exerciser-focused and has not considered how fitness professionals’ motivations impact their behaviors toward exercisers during training sessions. The purpose of this study was to examine the factor structure of the Coach Motivation Questionnaire in a sample of fitness professionals (CMQ-FP) to ascertain its usefulness for this vocational ...
The impact of forest clearance, and its replacement by Brachiaria pastures, on soil carbon reserves has been studied at many sites in the Brazilian Amazonia, but to date there appear to be no reports of similar studies undertaken in the Atlantic forest region of Brazil. In this study performed in the extreme south of Bahia, the changes in C and N content of the soil were evaluated from the time of establishment...
Hidradenitis suppurativa (HS) is a chronic, recurrent and debilitating skin disease of the hair follicle that is accompanied by systemic inflammation. Treating HS is challenging, and therapeutic tools as diverse as topical and systemic antibiotics, biologics, intralesional steroids, surgical procedures or light and laser therapies are frequently needed. The combination of oral clindamycin and rifampicin has bee...