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Prognostic factors in patients with advanced differentiated thyroid cancer trea...

Treistman,Natalia; Nobre,Gabriela Maia; Tramontin,Mariana Yoshii; Silva,Gabriel Madeira Werberich da; Herchenhorn,Daniel; Araujo,Luiz Henrique de Lima

ABSTRACT Objective: The aim of this study was to describe the real-world experience multikinase inhibitors (MKI) in the treatment advanced differentiated thyroid carcinoma (DTC) refractory to radioactive iodine (RAIR) therapy. Subjects and methods: We reviewed the records of all patients with MKI-treated DTC from 2010 to 2018. Progression free survival (PFS), response rates (RR) and adverse events (AE) profiles...

Date: 2021   |   Origin: Oasisbr

Pregnancy has no significant impact on the prognosis of differentiated thyroid ...

Nobre,Gabriela Maia; Tramontin,Mariana Yoshii; Treistman,Natalia; Alves Junior,Paulo Alonso; Andrade,Fernanda Accioly; Bulzico,Daniel Alves

ABSTRACT Objective: To evaluate the impact of pregnancy on differentiated thyroid carcinomas (DTC) behavior Subjects and methods: Retrospective study of patients diagnosed with DTC before or during pregnancy and treated with standard therapy. In women diagnosed with DTC before pregnancy, we evaluated the occurrence of progression according to categories of response to therapy based on imaging and non-stimulated...

Date: 2021   |   Origin: Oasisbr

Cholestatic syndrome as initial manifestation of pancreatic metastasis of papil...

Tramontin,Mariana Yoshii; Faria,Paulo Antônio Silvestre de; Nascimento,Cristina Moreira do; Barbosa,Cibele de Aquino; Barros,Maria de Fátima Rei Pereira

SUMMARY Most papillary thyroid carcinomas (PTC) harbor excellent prognosis. Although rare, distant metastases normally occur in lungs and/or bones. Here we describe a rare case of pancreatic metastasis presenting with rapid onset cholestatic syndrome. A literature review was also performed. A 73-year-old man with a high risk PTC was submitted to total thyroidectomy (TT) followed by radioiodine therapy. After in...

Date: 2020   |   Origin: Oasisbr

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