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Subnational mapping of HIV incidence and mortality among individuals aged 15–49...

Sartorius, B; VanderHeide, JD; Yang, M; Goosmann, EA; Hon, J; Haeuser, E; Cork, MA; Perkins, S; Jahagirdar, D; Schaeffer, LE; Serfes, AL; LeGrand, KE

Background. High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and efficiency of targeting efforts. We aimed to assess HIV incidence and HIV mortality for all second-level administrative units across sub-Saharan Africa. Methods. In this modelling study, we devel...


Anemia prevalence in women of reproductive age in low- and middle-income countr...

Kinyoki, D; Osgood-Zimmerman, AE; Bhattacharjee, NV; Schaeffer, LE; Lazzar-Atwood, A; Lu, D; Ewald, SB; Donkers, KM; Letourneau, ID; Collison, M

Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate results to policy-relevant administrative and national levels. Addi...


Therapeutic potential of rosmarinic acid: A comprehensive review

Nadeem, M; Imran, M; Gondal, TA; Imran, A; Shahbaz, M; Amir, RM; Sajid, MW; Qaisrani, TB; Atif, M; Hussain, G; Salehi, B; Ostrander, EA; Martorell, M

Naturally occurring food-derived active ingredients have received huge attention for their chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) is a caffeic acid ester and a naturally-occurring phenolic compound in a number of plants belonging to the Lamiaceae family, such as Rosmarinus officinalis (rosemary) from which it was formerly isolated. RA intervenes in carcinogenesis...


Kaempferol: A Key Emphasis to Its Anticancer Potential

Imran, M; Salehi, B; Sharifi Rad, J; Gondal, TA; Saeed, F; Imran, A; Shahbaz, M; Fokou, PVT; Arshad, MU; Khan, H; Susana Guerreiro; Martins, N

A marked decrease in human cancers, including breast cancer, bone cancer, and cervical cancer, has been linked to the consumption of vegetable and fruit, and the corresponding chemoprotective effect has been associated with the presence of several active molecules, such as kaempferol. Kaempferol is a major flavonoid aglycone found in many natural products, such as beans, bee pollen, broccoli, cabbage, capers, c...


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