14 documents found, page 1 of 2
Pregnancy outcomes in systemic sclerosis: experience of a rheumatology-obstetri...
Chícharo, Ana Teodósio; Lopes, Ana Rita; Barreira, Sofia; Martins, Patrícia; Machado, Ana Rita Cruz; Pinto, Luísa; Capela, SusanaSystemic sclerosis (SSc) is a rare multisystemic connective tissue disease (CTD). It is mainly characterized by progressive fibrosis and non-inflammatory vasculopathy. Women diagnosed with SSc seem to be at increased risk of developing adverse pregnancy outcomes (APO), but maternal and perinatal outcomes remain poorly understood in these patients, with no data yet available from Portuguese centers.
Maternal and perinatal outcomes in pregnant women with rheumatic diseases treat...
Chícharo, Ana Teodósio; Lopes, Ana R.; Barreira, Sofia; Pinto, Luísa; Machado, Ana R. Cruz; Capela, SusanaNo safety or efficacy issues arose from using biosimilar TNFi during conception or pregnancy.
ERN ReCONNET points to consider for treating patients living with autoimmune rh...
Talarico, Rosaria; Ramirez, Giuseppe Alvise; Barreira, Sofia; Cardamone, Chiara; Triggianese, Paola; Aguilera, Silvia; Andersen, Jeanette; Avcin, TadejRecent studies have shown that people who are immunocompromised may inadvertently play a role in spurring the mutations of the virus that create new variants. This is because some immunocompromised individuals remain at risk of getting COVID-19 despite vaccination, experience more severe disease, are susceptible to being chronically infected and remain contagious for longer if they become infected and consideri...
Predictors of cardiac involvement in idiopathic inflammatory myopathies
Bandeira, Matilde; Dourado, Eduardo; Melo, Ana Teresa; Martins, Patrícia; Fraga, Vanessa; Ferraro, José Luís; Saraiva, André; Sousa, MarleneObjectives: Idiopathic inflammatory myopathies (IIM) are a group of rare disorders that can affect the heart. This work aimed to find predictors of cardiac involvement in IIM. Methods: Multicenter, open cohort study, including patients registered in the IIM module of the Rheumatic Diseases Portuguese Register (Reuma.pt/Myositis) until January 2022. Patients without cardiac involvement information were excluded....
Epipericardial fat necrosis in chest CT and MRI: a case report of an unusual ca...
Barreto, Inês; Oliveira, Francisca Godinho; Barreira, Sofia; Inácio, João R.Background: Epipericardial fat necrosis (EFN) is a benign and self-limited condition of unknown cause with a good prognosis, usually affecting otherwise healthy patients. Clinically, it presents with severe acute left pleuritic chest pain, often leading the patient to the Emergency Room (ER). Case presentation: A 23-year-old male, smoker (5 pack-years), was evaluated in the ER due to left pleuritic chest pain, ...
Ultrasound findings and prognosis of shoulder pain: a role for Doppler signal?
Janeiro, João; Barreira, Sofia; Martins, Patrícia; Sarmento, Marco; Campos, Jorge; Fonseca, João EuricoPurpose: To find ultrasound prognostic factors for shoulder pain. Methods: This was an observational, prospective study, comparing the evolution of ultrasound findings with clinical outcomes, in patients with shoulder pain. Data were collected in two appointments, from February 2018 to March 2021. Two-tailed non-parametric statistics were used, and p values <0.05 were considered significant. Results: A total of...
Risk factors for infection, predictors of severe disease, and antibody response...
Machado, Ana Rita; Barreira, Sofia; Bandeira, Matilde; Veldhoen, Marc; Gomes, Andreia; Serrano, Marta; Duarte, Catarina; Rato, MariaObjective: To identify risk factors for SARS-CoV-2 infection and for severe/critical COVID-19, and to assess the humoral response after COVID-19 in these patients. Methods: Nationwide study of adult patients with inflammatory RMDs prospectively followed in the Rheumatic Diseases Portuguese Register-Reuma.pt-during the first 6 months of the pandemic. We compared patients with COVID-19 with those who did not deve...
Different antibody-associated autoimmune diseases have distinct patterns of T f...
Ribeiro, Filipa; Romão, Vasco C.; Rosa, Sara; Jesus, Kátia; Agua-Doce, Ana; Barreira, Sofia; Martins, Patrícia; Silva, Susana; Nobre, EmaAutoantibodies are produced within germinal centers (GC), in a process regulated by interactions between B, T follicular helper (Tfh), and T follicular regulatory (Tfr) cells. The GC dysregulation in human autoimmunity has been inferred from circulating cells, albeit with conflicting results due to diverse experimental approaches. We applied a consistent approach to compare circulating Tfr and Tfh subsets in pa...
Connective tissue disease as a cause of discrepant capillary and serum glucose ...
Matos, Tânia; Rocha, José Vicente; Barreira, Sofia; Vale, Sónia do; Bugalho, Maria JoãoCapillary glucose measurement is widely used for point-of-care testing and for self-monitoring of blood glucose. Nevertheless, fingertip capillary glucose assessment has some limitations and could lead to erroneous estimations in several situations, such as problems associated with certain medications or conditions related to hyperviscosity or to impaired capillary blood flow.
Rare clinical manifestations in systemic lupus erythematosus: a review on frequ...
Tani, Chiara; Elefante, Elena; Arnaud, Laurent; Barreira, Sofia; Bulina, Inita; Cavagna, Lorenzo; Costedoat-Chalumeau, Nathalie; Doria, AndreaObjectives: The purpose of this study was to review the frequency and clinical presentation of the rarest clinical manifestations of systemic lupus erythematosus (SLE). Methods: A list of 6 rare SLE manifestations were defined: gastrointestinal, liver, pulmonary, cardiac, ocular and neurological manifestations. Each topic was assigned to a pair of authors to perform a literature search and article review. Resul...