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Early ART in Acute HIV-1 Infection: Impact on the B-Cell Compartment
Badura, Robert; Foxall, Russell B.; Ligeiro, Dario; Rocha, Miguel; Godinho-Santos, Ana; Trombetta, Amelia C.; Sousa, Ana E.HIV-1 infection induces B cell defects, not fully recovered upon antiretroviral therapy (ART). Acute infection and the early start of ART provide unique settings to address the impact of HIV on the B cell compartment. We took advantage of a cohort of 21 seroconverters, grouped according to the presence of severe manifestations likely mediated by antibodies or immune complexes, such as Guillain-Barré syndrome an...
Date: 2020
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Origin: Grupo de Ativistas em Tratamentos