3 documents found, page 1 of 1
Sickle cell trait in São Tomé e Príncipe: a population-based prevalence study i...
Queiroz, Guilherme; Monteiro, Celdidy; Manco, Licínio; Relvas, Luís; Trovoada, Maria de Jesus; Leite, Andreia; Bento, CelesteBackground Sickle Cell Disorder is Africa’s most prevalent genetic disease. Yet, it remains a neglected condition, with high mortality under-five, and a lack of population-based studies in the region. This is the first of its kind in São Tomé e Príncipe, aiming to estimate the prevalence of sickle cell trait and other haemoglobin variants in women of reproductive age and its associated factors. Methods: We cond...
Analysis of TPI gene promoter variation in three sub-Saharan Africa population ...
Manco, Licínio; Machado, Patrícia; Lopes, Dinora; Nogueira, Fátima; Rosário, Virgílio E. do; Alonso, Pedro L.; Varandas, Luís; Trovoada, Maria de JesusPopulation samples from Angola, Mozambique, and S. Tomé e Príncipe were screened for the TPI gene promoter variants -5ArarrG, -8GrarrA and -24TrarrG. Three haplotypes were identified in the three populations: the haplotype -5A-8G-24T (average frequency 65.3%) and two less common haplotypes -5G-8G-24T (average frequency 24.7%) and -5G-8A-24T (average frequency 10.0%). A population sample from Central Portugal sh...
STR data from S. Tomé e Príncipe (Gulf of Guinea, West Africa)
Gusmão, Leonor; Prata, Maria João; Miranda, Carlos; Trovoada, Maria de Jesus; Amorim, AntónioAllele frequencies for eight STRs (CD4, FES/FPS, MBPB, TH01, TP53, TPO, F13A1, VWA) were estimated from samples (sized between 279 and 328) of unrelated individuals born in S. Tomé e Príncipe (Gulf of Guinea, West Africa).; http://www.sciencedirect.com/science/article/B6T6W-41WJBSP-8/1/a84a6eb4f309df8255225fa49f985dd7