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Signal-carrying speckle in optical coherence tomography: a methodological revie...

Silva, Vânia B.; Jesus, Danilo Andrade de; Klein, Stefan; van Walsum, Theo; Cardoso, João M.; Brea, Luisa Sánchez; Vaz, Pedro G.

Significance: Speckle has historically been considered a source of noise in coherent light imaging. However, a number of works in optical coherence tomography (OCT) imaging have shown that speckle patterns may contain relevant information regarding subresolution and structural properties of the tissues from which it is originated. Aim: The objective of this work is to provide a comprehensive overview of the met...


Aβ and NMDAR activation cause mitochondrial dysfunction involving ER calcium re...

Ferreira, Ildete Luísa; Ferreiro, Elisabete; Schmidt, Jeannette; Cardoso, João M.; Pereira, Cláudia M. F.; Carvalho, Ana Luísa; Oliveira, Catarina R.


Dead-time analysis of digital spectrometers

Cardoso, João M.; Simões, J. Basílio; Correia, Carlos M. B. A.

This paper studies the impact that the outcome of new digital architectures has brought to dead time of spectrometers. Special emphasis is given to the performance comparison between conventional spectrometers and the most important architectures usually adopted in the digital solutions. Dead-time analysis is accomplished through a dedicated numerical simulation application developed with the purpose of optimiz...


CdZnTe spectra improvement through digital pulse amplitude correction using the...

Cardoso, João M.; Simões, J. Basílio; Menezes, Tiago; Correia, Carlos M. B. A.

This paper presents innovative algorithms for optimum filtering, rise-time discrimination and proper correction of solid-state detector pulses based on digital pulse processing (DPP) techniques and on a Linear Sliding Method. These techniques allow a significant improvement on the spectral resolution by taking into account both the electronic noise and the pulse rise time fluctuations mainly due to the incomple...


Energy linearity response of CZT detectors to X-rays in the region of the Zn, C...

Freitas, E. D. C.; Cardoso, João M.; Fernandes, L. M. P.; Lopes, J. A. M.; Veloso, J. F. C. A.; Santos, J. M. F. dos

The response of a cadmium zinc telluride (CZT) detector to X-rays with energies around the Zn, Cd and Te K-absorption edges was investigated. The energy non-linearity in the detector response at the K-edges is less than 0.1%, within the experimental errors. No abrupt variation in both the w-value and the detector energy resolution was observed at the K-edges, a behaviour consistent with the absence of intrinsic...


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