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Naturally Occurring Bioactives as Antivirals: Emphasis on Coronavirus Infection

Ayatollahi, SA; Sharifi-Rad, J; Tsouh Fokou, PV; Mahady, GB; Ansar Rasul Suleria, H; Krishna Kapuganti, S; Gadhave, K; Giri, R; Garg, N; Sharma, R

The current coronavirus disease (COVID-19) outbreak is a significant threat to human health and the worldwide economy. Coronaviruses cause a variety of diseases, such as pneumonia-like upper respiratory tract illnesses, gastroenteritis, encephalitis, multiple organ failure involving lungs and kidneys which might cause death. Since the pandemic started there have been more than 107 million COVID-19 infections ca...


Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysi...

Sharifi-Rad, M; Anil Kumar, NV; Zucca, P; Varoni, EM; Dini, L; Panzarini, E; Rajkovic, J; Tsouh Fokou, PV; Azzini, E; Peluso, I; Prakash Mishra, A

Oxidative stress plays an essential role in the pathogenesis of chronic diseases such as cardiovascular diseases, diabetes, neurodegenerative diseases, and cancer. Long term exposure to increased levels of pro-oxidant factors can cause structural defects at a mitochondrial DNA level, as well as functional alteration of several enzymes and cellular structures leading to aberrations in gene expression. The modern...


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