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A Preliminary Evaluation of the Pro-Chondrogenic Potential of 3D-Bioprinted Pol...

Moxon, Samuel R.; Ferreira, Miguel J. S.; Santos, Patrícia dos; Popa, Bogdan; Gloria, Antonio; Katsarava, Ramaz; Tugushi, David; Serra, Arménio C.

Degeneration of articular cartilage (AC) is a common healthcare issue that can result in significantly impaired function and mobility for affected patients. The avascular nature of the tissue strongly burdens its regenerative capacity contributing to the development of more serious conditions such as osteoarthritis. Recent advances in bioprinting have prompted the development of alternative tissue engineering t...


Towards the development of electrospun mats from poly(ε-caprolactone)/poly(este...

Lamas, Miguel; Lima, Mafalda S.; Pinho, AC; Tugushi, David; Katsarava, Ramaz; Costa, Elisabete C.; Correia, Ilídio Joaquim Sobreira; Serra, Armenio

In this work, electrospun mats made from miscible poly(ε-caprolactone) (PCL)/poly(ester amide) (PEA) blends were prepared, for the first time. The well-known immiscibility issues between these two type of polymers were overcome through the synthesis of a novel tailor-made compatibilizer blocky PEA, comprising well defined PCL and PEA8L6 blocks (PCL-PEA8L6). The PCL-PEA8L6 was synthesized for the first time in t...

Date: 2018   |   Origin: uBibliorum

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