4 documents found, page 1 of 1
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Diso...
Mullins, Niamh; Kang, JooEun; Campos, Adrian I; Coleman, Jonathan R I; Edwards, Alexis C; Galfalvy, Hanga; Levey, Daniel F; Lori, AdrianaBackground: Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods: We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) c...
Analysis of shared heritability in common disorders of the brain
Anttila, Verneri; Bulik-Sullivan, Brendan; Finucane, Hilary K.; Walters, Raymond K.; Bras, Jose; Duncan, Laramie; Escott-Price, ValentinaDisorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain disorders from genome-wide association studies of 265,218 patients and 784,643 control participants and assessed their relationship to 17 phenotypes from 1,191,588 individuals. Psychiatric disorders share common varian...
Alcohol and cigarette use and misuse among hurricane Katrina survivors: Psychos...
Flory, Kate; Hankin, Benjamin L.; Kloos, Bret; Cheely, Catherine; Turecki, GustavoThe present study examined survivors’ use and misuse of cigarettes and alcohol following Hurricane Katrina. We also examined several psychosocial factors that we expected would be associated with higher or lower rates of substance use following the Hurricane. Participants were 209 adult survivors of Hurricane Katrina interviewed in Columbia, SC or New Orleans, LA between October 31, 2005 and May 13, 2006. Resul...
Are coping strategies, social support, and hope associated with psychological d...
Glass, Kerrie; Flory, Kate; Hankin, Benjamin L.; Kloos, Bret; Turecki, GustavoThis study examined the relation of coping strategies, social support, and hope to psychological distress [symptoms of posttraumatic stress disorder (PTSD) and general distress] among Hurricane Katrina survivors. The research questions concerned whether different coping strategies (problem-focused or avoidant coping), perceptions of social support, and hope were associated with psychological distress within thi...