21 documents found, page 1 of 3
Effect of thermal and chemical treatments used for SARS-COV-2 inactivation in t...
Lamy, Elsa; Rubio, Camila; Carreira, Laura; Capela e Silva, Fernando; Martinez-Subiela, Silvia; Tecles, Fernando; Lopez-Jornet, Pia; Céron, JoseThe present study aims to assess the effects of thermal and chemical inactivating procedures, that can be used for SARS-CoV-2 inactivation, on different salivary analytes. SDS-Polyacrylamide Gel Electrophoresis (SDS-PAGE) protein profile and a panel of 25 specific biomarkers of oxidative status, stress, metabolism and tissue damage were evaluated in samples subjected to different treatments: thermal (65 °C or 9...
Salivary Biomarkers in the Diagnosis and Monitoring of Metabolic and Endocrine ...
Tvarijonaviciute, Asta; Lucena, Sónia; Capela e Silva, Fernando; Lamy, ElsaThe present chapter revises the current knowledge about the use of salivary biomarkers for metabolic and endocrine disease diagnosis and monitoring in humans and different animal species. Currently, most information available comes from human medicine and studies performed with experimental animals such as mouse or rat, and less from other veterinary species. Furthermore, since obesity and its-related pathologi...
Saliva in Health and Disease - The Present and Future of a Unique Sample for Di...
Tvarijonaviciute, Asta; Martinez-Subiela, Silvia; Lopez-Jornet, Pia; Lamy, ElsaSaliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects in human and veterinary species. Once deemed merely a digestive juice is now considered a biological fluid capable of communicating information about physiopat...
Proteomics-based identification of salivary changes in patients with burning mo...
Castillo-Felipe, Candela; Franco-Martínez, Lorena; Tvarijonaviciute, Asta; Lopez-Jornet, Pia; Lamy, ElsaBurning mouth syndrome (BMS) is a chronic oral condition characterized by an intraoral burning sensation, taste alterations, and dry mouth sensations. Although a number of factors have been closely related to the appearance of the symptoms, including anxiety, depression, and sleep disturbances, the etiology of BMS remains unclear. Furthermore, currently no objective diagnostic tools exist, making its diagnosis ...
Analytical validation of an automated assay for the measurement of adenosine de...
Franco-Martinéz, Lorena; Tecles, Fernando; Torres-Cantero, A.; Bernal, E.; San-Lázaro, I.; Alcaraz, M.J.; Vicente-Romero, M.R.; Lamy, ElsaObjectives The aim of the present study was to validate a commercially available automated assay for the measurement of total adenosine deaminase (tADA) and its isoenzymes (ADA1 and ADA2) in saliva in a fast and accurate way, and evaluate the possible changes of these analytes in individuals with SARS-CoV-2 infection. Methods The validation, in addition to the evaluation of precision and accuracy, included the ...
The future of saliva as an analytical sample
Tvarijonaviciute, Asta; Martinéz-Subiela, Silvia; López-Jornet, Pia; Lamy, ElsaSaliva has gained attention in research mainly because of the noninvasive way in which the samples are obtained, allowing repeated sampling even in very susceptible populations such as children. Moreover, increasing scientific evidence confirms and highlights the potential of saliva as an analytical sample in application to both local and systemic diseases. Several aspects of saliva have been studied in the sea...
Salivary biomarkers in the diagnosis and monitoring of metabolic and endocrine ...
Tvarijonaviciute, Asta; Martinez-Subiela, Silvia; Lopez-Jornet, Pia; Lamy, ElsaThe present chapter revises the current knowledge about the use of salivary biomarkers for metabolic and endocrine disease diagnosis and monitoring in humans and different animal species. Currently, most information available comes from human medicine and studies performed with experimental animals such as mouse or rat, and less from other veterinary species. Furthermore, since obesity and its-related pathologi...
Changes in serum thiol-disulphide homeostasis in sheep with gastrointestinal ne...
Schmidt, Elizabeth Moreira dos Santos [UNESP]; Fachiolli, Daniele Floriano [UNESP]; de Oliveira, Raphaela Moreira [UNESP]Made available in DSpace on 2022-04-29T08:34:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); This work aimed to evaluate the thiol-disulphide homeostasis in serum of lambs naturally infected by gastrointestinal nematodes presenting different levels of parasite load indirectly indicated by faecal worm egg counts (EPG). Furthermore, t...
Comparative proteomic analysis of saliva from dogs with and without obesity-rel...
Lucena, Sónia; Coelho, Ana; Capela e Silva, Fernando; Lamy, Elsa; Tvarijonaviciute, AstaDogs develop only some of the components of the human metabolic syndrome (MetS). Thus, in order to study possible MetS-related alterations in dogs, human MetS criteria were adapted to define canine MetS or so-called obesity-related metabolic dysfunction (ORMD). The main objective of this study was to identify changes in the salivary proteome of obese dogs with ORMD in comparison with obese dogs without ORMD whi...
Obesidade Humana e Canina: Factores de Risco
Lucena, Sónia; Lavrador, Catarina; Infante, Paulo; Capela e Silva, Fernando; Tvarijonaviciute, Asta; Lamy, ElsaA prevalência da obesidade humana triplicou em muitos países da União Europeia desde os anos 80, permanecendo o seu aumento a um ritmo alarmante [1]. Nos cães de companhia observou-se, igualmente, um aumento da sua prevalência [1]. Apesar destas evidências, a situação em Portugal não está caracterizada em animais de companhia, e a relação entre as obesidades canina e humana não é conhecida para a população port...