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Influence of the timing of biological treatment initiation on Juvenile Idiopath...

Oliveira Ramos, Filipa; Maria Rodrigues, Ana; Melo, Ana Teresa; Aguiar, Francisca; Brites, Luísa; Azevedo, Soraia; Duarte, Ana Catarina

Funding Information: This study would not have been possible without the collaboration of numerous clinicians, patients, and their parents. Publisher Copyright: © 2023, BioMed Central Ltd., part of Springer Nature.; Background: Juvenile idiopathic arthritis (JIA) treatment is aimed at inducing remission to prevent joint destruction and disability. However, it is unclear what is the long-term impact on health-re...


Health-related quality of life and disability in adults with juvenile idiopathi...

Oliveira Ramos, Filipa; Maria Rodrigues, Ana; Magalhaes Martins, Fernando; Melo, Ana Teresa; Aguiar, Francisca; Brites, Luisa; Azevedo, Soraia

Objective To compare physical disability, mental health, fatigue and health-related quality of life (HRQoL) across juvenile idiopathic arthritis (JIA) categories in adulthood and between JIA and adult-onset rheumatic diseases. Methods Cross-sectional analysis nested in a cohort of adult patients with JIA registered in the Rheumatic Diseases Portuguese Register (Reuma.pt). Physical disability (Health Assessment ...


Genetic Predictors of Poor Prognosis in Portuguese Patients with Juvenile Idiop...

Mourão, Ana Filipa; Santos, Maria José; Mendonça, Sílvia; Oliveira-Ramos, Filipa; Salgado, Manuel; Estanqueiro, Paula; Melo-Gomes, José

Introduction. This study aimed to assess the genetic determinants of poor outcome in Portuguese patients with juvenile idiopathic arthritis (JIA). Methods. Our study was conducted in Reuma.pt, the Rheumatic Diseases Portuguese Register, which includes patients with JIA. We collected prospectively patient and disease characteristics and a blood sample for DNA analysis. Poor prognosis was defined as CHAQ/HAQ >0.7...


Using the juvenile arthritis disease activity score based on erythrocyte sedime...

Mourão, Ana Filipa; Santos, Maria J.; Melo-Gomes, José; Martins, Fernando M.; Costa, José A.; Ramos, Filipa; Brito, Iva; Duarte, Cátia

Objective Our aims were to evaluate the correlation between Juvenile Arthritis Disease Activity Score 27-joint reduced count (JADAS27) with erythrocyte sedimentation rate (ESR) and JADAS27 with C-reactive protein (CRP) scores and to test the agreement of both scores on classifying each disease activity state. We also aimed at verifying the correlation of the 2 scores across juvenile idiopathic arthritis (JIA) c...


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