Agradecimentos: This research was partially supported by Brazilian Research Council (CNPQ – National Council for Scientific and Technological Development); Abstract: Age-related macular degeneration (AMD) is a multifactorial disease and one of the main causes of blindness in people over 50 years old. The etiology and pathophysiology of AMD are not well understood. The aim of this study was to investigate whethe...
Agradecimentos: This study was supported by the Fund for Support to Teaching, Research and Outreach Activities (FAEPEX) grants 1525/15 and 251/18 and by S~ao Paulo Research Foundation (FAPESP) grant 2010/18353–9; Abstract: This study aimed to investigate the association among genetic variants of the complement pathway CFB R32Q (rs641153), C3 R102G (rs2230199), and CFH (rs1410996) with age-related macular degene...
Agradecimentos: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by the Fund for Support to Teaching, Research and Outreach Activities (FAEPEX) grants 1525/15 and 251/18 and by S~ao Paulo Research Foundation (FAPESP) grant 2010/18353–9; Abstract: This study aimed to evaluate the role of APOE polymorphism...
Agradecimentos: São Paulo Research Foundation, FAPESP (grant 2010/18353-9); Abstract: Background: Primary open-angle glaucoma (POAG) is a multifactorial disease that affects 65.5 million people worldwide. In addition to the genetic variants already established as indicators of greater risk for POAG, the apolipoprotein (APOE) gene has been studied in some populations, with controversial results. The aim of this ...