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Promising anticancer agents based on 8-hydroxyquinoline hydrazone copper(II) co...

Ribeiro, Nádia; Bulut, Ipek; Sergi, Baris; Pósa, Vivien; Spengler, Gabriella; Sciortino, Giuseppe; André, Vânia; Ferreira, Liliana P.; Biver, Tarita

We report the synthesis and characterization of a group of benzoylhydrazones (Ln) derived from 2-carbaldehyde-8-hydroxyquinoline and benzylhydrazides containing distinct para substituents (R = H, Cl, F, CH3, OCH3, OH and NH2, for L1-7, respectively; in L8 isonicotinohydrazide was used instead of benzylhydrazide). Cu(II) complexes were prepared by reaction of each benzoylhydrazone with Cu(II) acetate. All compou...


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