Treatment of drug-resistant tuberculosis requires extended use of more toxic and less effective drugs and may result in retreatment cases due to failure, abandonment or disease recurrence. It is therefore important to understand the evolutionary process of drug resistance in Mycobacterium tuberculosis. We here in describe the microevolution of drug resistance in serial isolates from six previously treated patie...
Genomic-based surveillance on the occurrence of drug resistance and its transmission dynamics has emerged as a powerful tool for the control of tuberculosis (TB). A whole-genome sequencing approach, phenotypic testing and clinical-epidemiological investigation were used to undertake a retrospective population-based study on drug-resistant (DR)-TB in Rio Grande do Sul, the largest state in Southern Brazil. The a...
Foram analisados soromicologicamente, para histoplasmose e paracoccidioidomicose, 65 pacientes em teste terapêutico para tuberculose pulmonar e/ou pleural, no período de março a julho de 1998, atendidos no Centro de Saúde Modelo (Secretaria de Saúde e do Meio Ambiente) em Porto Alegre. Entre os pacientes, foi identificado um caso de histoplasmose disseminada em paciente com Aids, no segundo teste terapêutico pa...
Submitted by Cristina Damasceno (damascenocris2011@gmail.com) on 2012-10-09T21:48:23Z No. of bitstreams: 1 Fungus ball in HIV-infected patients.pdf: 278854 bytes, checksum: d8fa3856fb580ce5046f5f97301d30c5 (MD5); Approved for entry into archive by Gabriela Silva da Rosa(gabrielasilvadarosa@gmail.com) on 2012-10-15T19:21:52Z (GMT) No. of bitstreams: 1 Fungus ball in HIV-infected patients.pdf: 278854 bytes, check...
KEYWORKS Tuberculosis, Primary Care, Family Health; -
Aspergillus is a phagocyte opportunistic fungus that causes aspergillosis, an unusual disease in patients with AIDS. Six cases of fungal ball in patients with AIDS are reported here. In this group, all patients had hemoptysis and tuberculosis as the underlying lung disease. The diagnosis of pulmonary fungus ball was based on the clinical and radiographic feature, combined with serological and mycological eviden...
Foram revisados 212 protocolos clínicos de pacientes com histoplasmose que constam nos arquivos do Laboratório de Micologia, Complexo Hospitalar Santa Casa, Porto Alegre (RS) num período de 25 anos (1977-2002). Aspectos epidemiológicos, clínicos, diagnósticos e terapêuticos foram estudados. Cento e cinquenta e seis casos de histoplasmose provenientes do Rio Grande do Sul nas suas diversas apresentações foram se...