3 documents found, page 1 of 1
Are Nanobiosensors an Improved Solution for Diagnosis of Leishmania?
Jain, Sona; Santana, Wanessa; Dolabella, Silvio S.; Santos, André L. S.; Souto, Eliana B.; Severino, PatríciaLeishmaniasis is one of the deadliest neglected tropical diseases affecting 12-15 million people worldwide, especially in middle- and low-income countries. Rapid and accurate diagnosis of the disease is important for its adequate management and treatment. Several techniques are available for the diagnosis of leishmaniasis. Among these, parasitological and immunological tests are most widely used. However, in mo...
Exploring innovative Leishmaniasis treatment: drug targets from pre-clinical to...
Santana, Wanessa; de Oliveira, Simone S. C.; Ramos, Mariana H.; Santos, André L. S.; Dolabella, Silvio S.; Souto, Eliana B.; Severino, PatríciaLeishmaniasis is a group of tropical diseases caused by parasitic protozoa belonging to the genus Leishmania. The disease is categorized in cutaneous leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), and visceral leishmaniasis (VL). The conventional treatment is complex and can present high toxicity and therapeutic failures. Thus, there is a continuing need to develop new treatments. In this review, we foc...
Are nanobiosensors an improved solution for diagnosis of Leishmania?
Jain, Sona; Santana, Wanessa; Dolabella, Silvio S.; Santos, André L. S.; Souto, Eliana B.; Severino, PatríciaLeishmaniasis is one of the deadliest neglected tropical diseases affecting 1215 million people worldwide, especially in middle- and low-income countries. Rapid and accurate diagnosis of the disease is important for its adequate management and treatment. Several techniques are available for the diagnosis of leishmaniasis. Among these, parasitological and immunological tests are most widely used. However, in mos...