10 documents found, page 1 of 1

Promising anticancer agents based on 8-hydroxyquinoline hydrazone copper(II) co...

We report the synthesis and characterization of a group of benzoylhydrazones (Ln) derived from 2-carbaldehyde-8-hydroxyquinoline and benzylhydrazides containing distinct para substituents (R = H, Cl, F, CH3, OCH3, OH and NH2, for L1-7, respectively; in L8 isonicotinohydrazide was used instead of benzylhydrazide). Cu(II) complexes were prepared by reaction of each benzoylhydrazone with Cu(II) acetate. All compou...

Scavenging of reactive oxygen species by phenolic compound-modified maghemite n...

Maghemite (γ-Fe2O3) nanoparticles obtained through co-precipitation and oxidation were coated with heparin (Hep) to yield γ-Fe2O3@Hep, and subsequently with chitosan that was modified with different phenolic compounds, including gallic acid (CS-G), hydroquinone (CS-H), and phloroglucinol (CS-P), to yield γ-Fe2O3@Hep-CS-G, γ-Fe2O3@Hep-CS-H, and γ-Fe2O3@Hep-CS-P particles, respectively. Surface modification of th...

Experimental data on novel Fe(III)-complexes containing phenanthroline derivati...

This dataset is related to the research article entitled "May iron(III) complexes containing phenanthroline derivatives as ligands be prospective anticancer agents?" [1]. It includes the characterization by UV-Vis absorption spectroscopy and magnetic techniques of a group of mixed ligand Fe(III) complexes bearing a tripodal aminophenolate ligand L2-, H2L = N,N-bis(2-hydroxy-3,5-dimethylbenzyl)-N-(2-pyridylmethy...

May iron(III) complexes containing phenanthroline derivatives as ligands be pro...

Made available in DSpace on 2019-10-06T17:10:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-15; Fundação para a Ciência e a Tecnologia; We report the design, synthesis and biological studies on a group of mixed ligand Fe(III) complexes as anti-cancer drug candidates, namely their interaction with DNA, cytotoxicity and mechanism(s) of action. The aim is to obtain stable, efficient and selective Fe-...

Selecting the spin crossover profile with controlled crystallization of mononuc...

Dynamic spin interchange in a tridentate Fe(iii) Schiff-base compound

The thermosalient effect is still a rare and poorly understood phenomenon, where crystals suddenly jump, bend, twist or explode upon undergoing a thermally activated phase transition. The synthesis and characterisation of the new spin transition Fe(iii) compound [Fe(5-Br-salEen)2][ClO4] (salEen = N-ethyl-N-(2-aminoethyl)salicylaldiminate) is described and its thermosalient behaviour reported. It is the first ex...

Gelatine-assisted synthesis of magnetite nanoparticles for magnetic hyperthermia

Magnetite nanoparticles were synthesized by the co-precipitation method exploring the use of gelatine and agar as additives. For comparison, magnetite nanoparticles were also prepared by standard co-precipitation, by co-precipitation with the addition of a surfactant (sodium dodecyl sulphate) and by the thermal decomposition method. The structure and morphology of the synthesized nanoparticles were investigated...

Solution and solid state properties of Fe(III) complexes bearing N-ethyl-N-(2-a...

The effect of the phenolate ring derivatisation on the magnetic properties of Fe(III) complexes bearing N-ethyl-N-(2-aminoethyl)salicylaldiminate ligands both in solid state and solution have been investigated. Two new complexes [Fe(3,5-Br-salEen)2]ClO4.EtOH (5) and [Fe(3,5-Br-salEen)2]BPh4.DMF (6) have been synthesised. SQUID magnetometry studies on these complexes showed that while complex 5 is in the low-spi...

Solution and solid state properties of Fe(III) complexes bearing N-ethyl-N-(2-a...

The effect of the phenolate ring derivatisation on the magnetic properties of Fe(III) complexes bearing Nethyl- N-(2-aminoethyl) salicylaldiminate ligands both in solid state and solution have been investigated. Two new complexes [Fe(3,5-Br-salEen)(2)]ClO4 center dot EtOH (5) and [Fe(3,5-Br-salEen)(2)]BPh4 center dot DMF (6) have been synthesised. SQUID magnetometry studies on these complexes showed that while ...

Synthesis and catalytic properties of manganese(II) and oxovanadium(IV) complex...

Reaction of [MnIII(acac)3] and [VIVO(acac)2] with the 1,4-diazabutadiene (DAB) ligands Ph-DAB-(CH2)3R [R = Si(OEt)3(1a); H (1b)] (L) leads to complexes of the type [MnII(acac)2L] and [VIVO(acac)L]Cl in good yields. These complexes were characterised by spectroscopic techniques, and magnetic measurements showed that in the case of the manganese the metal was reduced during the reaction with the nitrogen ligand.;...