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Loss of Raf kinase inhibitor protein expression is associated with human papill...

Bidinotto, Lucas Tadeu; Véo, Carlos A. R.; Loaiza, Edgar Aleman; Ribeiro, Guilherme G.; Lorenzi, Adriana T.; Rosa, Luciana Albina Reis

There has been an increase in the incidence of anal cancer in the past two decades, with squamous cell carcinoma (SCC) being the most frequent histological type identified. Among the risk factors, high-risk human papillomavirus (HPV) infection is the most pervasive. Raf kinase inhibitor protein (RKIP) is expressed in a number of normal human tissues and previous studies have demonstrated the prognostic value of...


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