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Relationship of the SITLESS intervention on medication use in community-dwellin...

Viegas, R; Alves da Costa, F; Mendes, R; Deidda, M; McIntosh, E; Sansano-Nadal, O; Magaña, JC; Rothenbacher, D; Denkinger, M; Caserotti, P; Tully, MA

Background: Sedentary behavior (SB) and physical activity (PA) interventions in older adults can improve health outcomes. Problems related with aging include prevalent comorbidity, multiple non-communicable diseases, complaints, and resulting polypharmacy. This manuscript examines the relationship between an intervention aiming at reducing SB on medication patterns. Method: This manuscript presents a local sub-...


Current Evidence on the Impact of Medication Optimization or Pharmacological In...

Pazan, F; Petrovic, M; Cherubini, A; Onder, G; Cruz-Jentoft, A; Denkinger, M; van der Cammen, T; Stevenson, J; Ibrahim, K; Rajkumar, C; Bakken, M

Background: Frailty and adverse drug effects are linked in the fact that polypharmacy is correlated with the severity of frailty; however, a causal relation has not been proven in older people with clinically manifest frailty. Methods: A literature search was performed in Medline to detect prospective randomized controlled trials (RCTs) testing the effects of pharmacological interventions or medication optimiza...


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