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The modulatory role of internet-supported mindfulness-based cognitive therapy o...

Pereira, Diana R.; Silva, Eunice R.; Carvalho-Maia, Carina; Monteiro-Reis, Sara; Lourenço, Catarina; Calisto, Rita; Teixeira, Ricardo João

Mindfulness-based interventions (MBIs) have been used in oncology contexts as a promising tool with numerous benefits for various health-related and psychosocial outcomes. Despite the increasing popularity of MBIs, few randomized controlled trials (RCTs) have examined their effects upon biological parameters. Specifically, no previous study has examined the effects of MBIs on extracellular vesicles (EVs), which...


The modulatory role of internet-supported mindfulness-based cognitive therapy o...

Pereira, Diana R.; Silva, Eunice R.; Carvalho-Maia, Carina; Monteiro-Reis, Sara; Lourenço, Catarina; Calisto, Rita; Teixeira, Ricardo João

Mindfulness-based interventions (MBIs) have been used in oncology contexts as a promising tool with numerous benefits for various health-related and psychosocial outcomes. Despite the increasing popularity of MBIs, few randomized controlled trials (RCTs) have examined their effects upon biological parameters. Specifically, no previous study has examined the effects of MBIs on extracellular vesicles (EVs), which...


Secreted Extracellular Vesicle Molecular Cargo as a Novel Liquid Biopsy Diagnos...

Monteiro-Reis, Sara; Carvalho-Maia, Carina; Bart, Genevieve; Vainio, Seppo J.; Pedro, Juliana; Silva, Eunice R.; Sales, Goreti; Henriques, Rui T.

Secreted extracellular vesicles (EVs) are heterogeneous cell-derived membranous granules which carry a large diversity of molecules and participate in intercellular communication by transferring these molecules to target cells by endocytosis. In the last decade, EVs' role in several pathological conditions, from etiology to disease progression or therapy evasion, has been consolidated, including in central nerv...


Secreted extracellular vesicle molecular cargo as a novel liquid biopsy diagnos...

Monteiro-Reis, Sara; Carvalho-Maia, Carina; Bart, Genevieve; Vainio, Seppo J.; Pedro, Juliana; Silva, Eunice R.; Sales, M. G. F.; Henrique, Rui

Secreted extracellular vesicles (EVs) are heterogeneous cell-derived membranous granules which carry a large diversity of molecules and participate in intercellular communication by transferring these molecules to target cells by endocytosis. In the last decade, EVs role in several pathological conditions, from etiology to disease progression or therapy evasion, has been consolidated, including in central nervo...


A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ure...

Chi, Lijun; Saarela, Ulla; Railo, Antti; Prunskaite-Hyyrylainen, Renata; Skovorodkin, Ilya; Anthony, Shelagh; Katsu, Kenjiro; Liu, Yu; Shan, Jingdong

The epithelial ureteric bud is critical for mammalian kidney development as it generates the ureter and the collecting duct system that induces nephrogenesis in dicrete locations in the kidney mesenchyme during its emergence. We show that a secreted Bmp antagonist Cerberus homologue (Cer1) fine tunes the organization of the ureteric tree during organogenesis in the mouse embryo. Both enhanced ureteric expressio...


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