11 documents found, page 1 of 2
Choosing Wisely for Thyroid Conditions: Recommendations of the Thyroid Departme...
Dora,Jose Miguel; Biscolla,Rosa Paula Mello; Caldas,Gustavo; Cerutti,Janete; Graf,Hans; Hoff,Ana O.; Mazeto,Glaucia M. F. S.ABSTRACT Objective: Choosing Wisely (CW) is an initiative that aims to advance the dialogue between physicians and patients about low-value health interventions. Given that thyroid conditions are frequent in clinical practice, we aimed to develop an evidence-based list of thyroid CW recommendations. Materials and methods: The Thyroid Department of the Brazilian Society of Endocrinology and Metabolism (SBEM) nam...
Management of thyroid disorders during the COVID-19 outbreak: a position statem...
Martins,João Roberto M.; Villagelin,Danilo G. P.; Carvalho,Gisah A.; Vaisman,Fernanda; Teixeira,Patrícia F. S.; Scheffel,Rafael S.; Sgarbi,José A.ABSTRACT This position statement was prepared to guide endocrinologists on the best approach to managing thyroid disorders during the coronavirus disease (COVID-19) pandemic. The most frequent thyroid hormonal findings in patients with COVID-19, particularly in individuals with severe disease, are similar to those present in the non-thyroidal illness syndrome and require no intervention. Subacute thyroiditis ha...
Prognostic factors in patients with advanced differentiated thyroid cancer trea...
Treistman,Natalia; Nobre,Gabriela Maia; Tramontin,Mariana Yoshii; Silva,Gabriel Madeira Werberich da; Herchenhorn,Daniel; Araujo,Luiz Henrique de LimaABSTRACT Objective: The aim of this study was to describe the real-world experience multikinase inhibitors (MKI) in the treatment advanced differentiated thyroid carcinoma (DTC) refractory to radioactive iodine (RAIR) therapy. Subjects and methods: We reviewed the records of all patients with MKI-treated DTC from 2010 to 2018. Progression free survival (PFS), response rates (RR) and adverse events (AE) profiles...
Pregnancy has no significant impact on the prognosis of differentiated thyroid ...
Nobre,Gabriela Maia; Tramontin,Mariana Yoshii; Treistman,Natalia; Alves Junior,Paulo Alonso; Andrade,Fernanda Accioly; Bulzico,Daniel AlvesABSTRACT Objective: To evaluate the impact of pregnancy on differentiated thyroid carcinomas (DTC) behavior Subjects and methods: Retrospective study of patients diagnosed with DTC before or during pregnancy and treated with standard therapy. In women diagnosed with DTC before pregnancy, we evaluated the occurrence of progression according to categories of response to therapy based on imaging and non-stimulated...
Cholestatic syndrome as initial manifestation of pancreatic metastasis of papil...
Tramontin,Mariana Yoshii; Faria,Paulo Antônio Silvestre de; Nascimento,Cristina Moreira do; Barbosa,Cibele de Aquino; Barros,Maria de Fátima Rei PereiraSUMMARY Most papillary thyroid carcinomas (PTC) harbor excellent prognosis. Although rare, distant metastases normally occur in lungs and/or bones. Here we describe a rare case of pancreatic metastasis presenting with rapid onset cholestatic syndrome. A literature review was also performed. A 73-year-old man with a high risk PTC was submitted to total thyroidectomy (TT) followed by radioiodine therapy. After in...
Serum calcitonin nadirs to undetectable levels within 1 month of curative surge...
Andrade,Fernanda; Rondeau,Geneviève; Boucai,Laura; Zeuren,Rebecca; Shaha,Ashok R.; Ganly,Ian; Vaisman,Fernanda; Corbo,Rossana; Tuttle,MichaelABSTRACT Objective: Because serum calcitonin (CT) is a reliable marker of the presence, volume, and extent of disease in medullary thyroid cancer (MTC), both the ATA and NCCN guidelines use the 2-3 month post-operative CT value as the primary response to therapy variable that determines the type and intensity of follow up evaluations. We hypothesized that the calcitonin would nadir to undetectable levels within...
Thyroid nodules ≤ 1 cm and papillary thyroid microcarcinomas: Brazilian experts...
Rosario,Pedro Weslley; Ward,Laura Sterian; Graf,Hans; Vaisman,Fernanda; Mourão,Gabriela Franco; Vaisman,MarioABSTRACT The indolent evolution of low-risk papillary thyroid microcarcinoma (mPTC) in adult patients and the consequences of thyroidectomy require a revision of the management traditionally recommended. Aiming to spare patients unnecessary procedures and therapies and to optimize the health system in Brazil, we suggest some measures. Fine-needle aspiration of nodules ≤ 1 cm without extrathyroidal extension on ...
Clinical outcomes of low and intermediate risk differentiated thyroid cancer pa...
Súss,Shirlei Kugler Aiçar; Mesa Jr.,Cleo Otaviano; Carvalho,Gisah Amaral de; Miasaki,Fabíola Yukiko; Chaves,Carolina Perez; Fuser,Dominique CochatABSTRACT Objective To retrospectively evaluate the outcomes of patients with low and intermediate risk thyroid carcinoma treated with total thyroidectomy (TT) and who did not undergo radioiodine remnant ablation (RRA) and to compare them to patients receiving low dose of iodine (30 mCi). Subjects and methods A total of 189 differentiated thyroid cancer (DTC) patients treated with TT followed by 30mCi for RRA or...
Metastatic lymph node characteristics as predictors of recurrence/persistence i...
Barbosa,Mayara Peres; Momesso,Denise; Bulzico,Daniel Alves; Farias,Terence; Dias,Fernando; Lima,Roberto Araújo; Corbo,Rossana; Vaisman,MarioABSTRACT Objective: The aim of this study was to evaluate the association between this characteristic and outcomes in patients with lymph node metastasis in a Brazilian cohort. Subjects and methods: This study examined a retrospective cohort of adult patients diagnosed with differentiated thyroid cancer and lymph node metastases from 1998 to 2015 in two referral centers. Number, location, size and extranodal ex...
Is radioactive iodine- 131 treatment related to the occurrence of non-synchrono...
Souza,Marcelo Cruzick de; Momesso,Denise P.; Vaisman,Fernanda; Vieira Neto,Leonardo; Martins,Rosangela Aparecida Gomes; Corbo,Rossana; Vaisman,MarioObjective Much controversy relates to the risk of non-synchronous second primary malignancies (NSSPM) after radioactive iodine treatment (RAI-131) in differentiated thyroid cancer (DTC) patients. This study evaluated the relationship between RAI-131 and NSSPM in DTC survivors with long-term follow-up. Materials and methods Retrospective analysis of 413 DTC cases was performed; 252 received RAI-131 and 161 were ...