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Abdominal Hypoperfusion and Acute Kidney Injury in the Critically Ill Patient w...

Pereira, Rui; Lopes, Diogo; Brandão Machado, Sara; Val-Flores, Luís; Caeiro, Fernando; Perdigoto, Rui; Marcelino, Paulo; Saliba, Faouzi

Reduced abdominal perfusion pressure (APP) is an underdiagnosed potential pathophysiological mechanism for acute kidney injury (AKI) in the patient with liver cirrhosis and ascites. This study aimed to analyze the prevalence of abdominal hypoperfusion (AhP) (APP <60 mm Hg) and the impact of APP on AKI in critically ill patients with liver cirrhosis. This was a post hoc analysis from a prospective cohort study s...


Fatal case of progressive Mpox in a patient with AIDS: viral enteropathy and ma...

Caria, João; Vara-Luiz, Francisco; Maia, Inês; Joosten, Anneke; Val-Flores, Luís; Pinheiro, Hélder; Póvoas, Diana; Germano, Nuno; Maltez, Fernando

We report a fatal case of disseminated mpox infection that progressed over more than three months in an HIV-infected patient with acquired immunodeficiency syndrome (AIDS). Mucocutaneous, pleuropulmonary, central nervous system, and gastrointestinal involvement was documented. This course of disease resembles progressive vaccinia, a formerly reported disease caused by uncontrolled replication of smallpox vaccin...


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