23 documents found, page 1 of 3

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Quercus spp. extract as a promising preventive or therapeutic strategy for canc...

Oliveira, Paula A.; Vasconcelos-Nóbrega, C; Pires, MJ; Vala, H; Barros, AIRNA; Faustino-Rocha, Ana I

Acorns have traditionally been used in the human diet and for the treatment of specific diseases. Therefore, the present study performed a systematic review of studies which investigated the effects of Quercus spp. extracts in cancer prevention and treatment. A systematic literature search was performed for original records which addressed the anticancer effects of Quercus spp. extract in in vitro and in vivo c...


Assessing the in vivo effects of Aloysia citrodora extract: data from K14-HPV16...

Medeiros-Fonseca, B; Vala, H; Vasconcelos-Nóbrega, C; Faustino-Rocha, Ana I; Medeiros, R; Bastos, MMSM; Gil da Costa, RM; Oliveira, PA

Introduction Aloysia citrodora is used in folk medicine in the preparation of infusions due to its antispasmodic, digestive, sedative, and antipyretic properties. It also has antioxidant and antimicrobial properties.The present study evaluated the in vivo efficacy of aqueous extract (AE) of Aloysia citrodora in K14-HPV16 transgenic mice which HPV16 early genomic region and hence develop multiple-step epithelial...


An antibody-based survey of Toxoplasma gondii and Neospora caninum infection in...

Aires Pereira, M; Nóbrega, C; Mateus, TL; Almeida, D; Oliveira, A; Coelho, C; Cruz, R; Oliveira, PA; Faustino-Rocha, AI; Pires, MJ; Mesquita, JR

Toxoplasma gondii and Neospora caninum are intracellular parasites with a great impact on human and animal health, respectively. This work aims to investigate the presence of antibodies against T. gondii and N. caninum in client-owned cats from Portugal and to identify risk factors. A total of 183 domestic cats were sampled and their owners answered an online questionnaire designed to obtain background informat...


Pulmonary and Gastrointestinal Parasitic Infections in Small Ruminant Autochtho...

Pereira, MA; Vila-Viçosa, MJ; Coelho, C; Santos, C; Esteves, F; Cruz, R; Gomes, L; Henriques, D; Vala, H; Nóbrega, C; Mega, AC; Melo, C; Malva, M

The production of small ruminant autochthonous breeds in the Centre region of Portugal is practiced in a semi-extensive husbandry system, exposing animals to parasitic infections. The main objective of this study was to estimate the prevalence of lungworm infection and identify risk factors. Fecal samples of 203 goats and 208 sheep from 30 herds were collected per rectum and subjected to the modified Baermann t...


Molecular evidence of sporadic Coxiella burnetii excretion in sheep milk, centr...

Pires, H; Santos-Silva, S; Cruz, AVS; Cardoso, L; Lopes, AP; Pereira, MA; Nóbrega, C; Mega, AC; Santos, C; Cruz, R; Esteves, F; Vala, H; Matos, AC

Coxiella burnetii is the etiologic agent of Q fever, a worldwide zoonosis. Cattle, sheep and goats are considered the main reservoirs of the disease. Transmission to humans occurs mainly through the inhalation of infectious aerosols from milk, faeces, urine, and birth products from infected ruminants. In this study, a 2-year longitudinal approach was performed to ascertain the excretion of C. burnetii in bulk t...


An Antibody-Based Survey of Toxoplasma gondii and Neospora caninum Infection in...

Pereira, MA; Nóbrega, C; Mateus, TL; Almeida, D; Oliveira, A; Coelho, C; Cruz, R; Oliveira, P; Faustino-Rocha, A; Pires, MJ; Mesquita, JR; Vala, H

Simple Summary Toxoplasma gondii and Neospora caninum are intracellular parasites with a great impact on human and animal health, respectively. This work aims to investigate the presence of antibodies against T. gondii and N. caninum in client-owned cats from Portugal and to identify risk factors. A total of 183 domestic cats were sampled and their owners answered an online questionnaire designed to obtain back...


Virtual physiology: a tool for the 21st Century

Nóbrega, C; Pereira, MA; Coelho C; Brás, C; Mega, AC; Santos, C; Esteves, F; Cruz, R; Faustino-Rocha, AI; Oliveira, PA; Mesquita, J; Vala, H

Veterinary physiology is a basic curricular unit for every course within the veterinary field. It is mandatory to understand how the animal body works, and what to expect of a healthy body, in order to recognize any misfunction, and to be able to treat it. Classic physiology teaching involves wet labs, much equipment, many reagents, some animals, and a lot of time. But times are changing. In the 21st century, i...


Prevalence of Toxoplasma gondii Antibodies in Individuals Occupationally Expose...

Almeida, D; Quirino, J; Matos, P; Esteves, F; Cruz, R; Vala, H; Mesquita, JR

Toxoplasmosis is a worldwide zoonotic disease with different and complex routes for transmission. Workers occupationally exposed to animals or raw meat and viscera (WOE) may be at more risk than the general population, however conflicting data exist on the risk of developing toxoplasmosis due to this close contact. To add knowledge to this topic, the aim of the present study was to ascertain if WOE were more li...


A Questionnaire-Based Survey on the Long-Term Management of Canine Leishmaniosi...

Pereira, MA; Santos, R; Nóbrega, C; Mega, C; Cruz, R; Esteves, F; Santos, C; Coelho, C; Mesquita, JR; Vala, H; Santos-Gomes, G

Canine Leishmaniosis (CanL) is a chronic and potentially fatal disease. In economically disadvantaged regions, costs associated with long-term patient monitoring may determine that some owners decline veterinary follow-up of their dogs. This online, questionnaire-based survey aimed to assess how Portuguese veterinary practitioners perform long-term patient monitoring and recognize relapses. More than 50% of res...


Rickettsia massiliae circulation in sheep and attached Rhipicephalus sanguineus...

Mesquita, JR; Santos-Silva, S; de Sousa Moreira, A; Baptista, MB; Cruz, R; Esteves, F; Vala, H; Barradas, PF

Rickettsiosis is considered an emerging/re-emerging vector-borne disease that causes significant public health threats. Ticks are reservoirs and vectors of Rickettsia having a significant role in the transmission of rickettsiae. In Portugal, little is known about tick-borne Rickettsia species in sheep. Therefore, this study aimed to investigate rickettsiae infection in ticks and their sheep host from 27 farms i...


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