26 documents found, page 1 of 3
Use of rectal balloon spacer in patients with localized prostate cancer receivi...
Costa, P; Vale, J; Fonseca, G; Costa, A; Kos, MObjective: To evaluate the efficacy of the balloon spacer when used to reduce the radiation dose delivered to the rectum in prostate cancer patients undergoing external beam radiotherapy. Method: A single center retrospective analysis including 75 PC patients with localized T1-T3a disease who received balloon spacer followed by EBRT. Pre- and post-implantation computed tomography (CT) scans were utilized for tr...
Consensus for the Early Identification of Secondary Progressive Multiple Sclero...
Sá, MJ; Basílio, C; Capela, C; Cerqueira, JJ; Mendes, I; Morganho, A; Correia de Sá, J; Salgado, V; Martins Silva, A; Vale, J; Sousa, LIntroduction: Multiple sclerosis is a disease with a heterogeneous evolution. The early identification of secondary progressive multiple sclerosis is a clinical challenge, which would benefit from the definition of biomarkers and diagnostic tools applicable in the transition phase from relapsing-remitting multiple sclerosis to secondary progressive multiple sclerosis. We aimed to reach a Portuguese national con...
Cognitive impairment and markers of optical neurodegeneration in early multiple...
Silva, R; Coelho, P; Seabra, M; Laranjinha, I; Vieira, D; Costa, O; Jesus, J; Fonseca, AC; Costa, S; Ferreira, I; Lemos, J; Sousa, C; Vale, J; Sá, MJIntroduction: Cognitive impairment and retinal atrophy have been proposed as two potential markers of neurodegeneration in multiple sclerosis (MS). We aimed at assessing the relation between peripapillary retinal nerve fiber layer (pRNFL) and macular ganglion cell layer (mGCL) atrophy and cognitive performance in early MS. Methods: This is a multicenter cross-sectional study on patients with early MS (clinicall...
Multiple Sclerosis Patient Management During the COVID-19 Pandemic: Practical R...
Cerqueira, J; Ladeira, A; Silva, AM; Timóteo, A; Vale, J; Sousa, L; Arenga, M; Abreu, P; Guerreiro, R; Sá, JThe spread of the COVID-19 pandemic has imposed significant challenges on healthcare provision, requiring changes in the conventional patient management, particularly in chronic diseases like multiple sclerosis (MS). To increase patient safety and reduce the risk of infection, while ensuring an appropriate and regular follow-up, tele-medicine gained prominence as a valid alternative to face-to-face appointments...
Digital pathology workflow implementation at ipatimup
Eloy, C; Vale, J; Curado, M; Polónia, A; Campelos, S; Caramelo, A; Sousa, R; Sobrinho-Simões, MThe advantages of the digital methodology are well known. In this paper, we provide a detailed description of the process for the digital transformation of the pathology laboratory at IPATIMUP, the major modifications that operate throughout the processing pipeline, and the advantages of its implementation. The model of digital workflow implementation at IPATIMUP demonstrates that careful planning and adoption ...
Consensus Recommendations of the Multiple Sclerosis Study Group and the Portugu...
Pereira, DJ; Abreu, P; Reis, AM; Seixas, D; Carreiro, I; Cravo, I; Graça, J; Freitas, PM; Brito, O; Silva, S; Vale, J; Vilela, PIntroduction: Magnetic resonance imaging is recognized as the most important diagnostic test in the diagnosis of multiple sclerosis, differential diagnosis and evaluation of progression/therapeutic response. However, to make optimal use of magnetic resonance imaging in multiple sclerosis, the use of a standard, reproducible and comparable imaging protocol is of uttermost importance. In this context, the Portugu...
Consensus Recommendations of the Multiple Sclerosis Study Group and the Portugu...
Pereira, DJ; Abreu, P; Reis, AM; Seixas, D; Carreiro, I; Cravo, I; Graça, J; Freitas, PM; Brito, O; Silva, S; Vale, J; Vilela, PINTRODUCTION: Magnetic resonance imaging is recognized as the most important diagnostic test in the diagnosis of multiple sclerosis, differential diagnosis and evaluation of progression/therapeutic response. However, to make optimal use of magnetic resonance imaging in multiple sclerosis, the use of a standard, reproducible and comparable imaging protocol is of uttermost importance. In this context, the Portugu...
A Multicenter, Non-Interventional Study to Evaluate the Disease Activity in Mul...
Ladeira, F; Braz, L; Salgado, P; Vaz, S; Leitão, L; Félix, C; Correia, AS; Martins da Silva, A; Salgado, V; Ferreira, F; Vale, J; Sá, MJ; Capela, CObjectives: Natalizumab (NTZ) is very effective for treatment of relapsing-remitting multiple sclerosis (RRMS), its use is mainly limited by safety issues. Discontinuation of NTZ is associated with recurrence of disease activity (reactivation and rebound). The best strategy for subsequent therapy and the predictive factors for recurrence in such patients are areas of active research. We aimed to evaluate predic...
Consensus Recommendations of the Multiple Sclerosis Study Group and Portuguese ...
Abreu, P; Pedrosa, R; Sá, MJ; Cerqueira, J; Sousa, L; Martins da Silva, A; Pinheiro, J; De Sá, J; Batista, S; Moiron Simões, R; Jardim Pereira, DINTRODUCTION: Magnetic resonance imaging is established as a recognizable tool in the diagnosis and monitoring of multiple sclerosis patients. In the present, among multiple sclerosis centers, there are different magnetic resonance imaging sequences and protocols used to study multiple sclerosis that may hamper the optimal use of magnetic resonance imaging in multiple sclerosis. In this context, the Group of St...
Consensus Recommendations of the Multiple Sclerosis Study Group and Portuguese ...
Abreu, P; Pedrosa, R; Sá, MJ; Cerqueira, J; Sousa, L; Da Silva, AM; Pinheiro, J; De Sá, J; Batista, S; Simões, RM; Pereira, DJ; Vilela, P; Vale, JINTRODUCTION: Magnetic resonance imaging is established as a recognizable tool in the diagnosis and monitoring of multiple sclerosis patients. In the present, among multiple sclerosis centers, there are different magnetic resonance imaging sequences and protocols used to study multiple sclerosis that may hamper the optimal use of magnetic resonance imaging in multiple sclerosis. In this context, the Group of St...