4 documents found, page 1 of 1
Effects of electroacupuncture on experimental periodontitis in rats
Lisboa, Mario R. P.; Gondim, Delane V.; Ervolino, Edilson; Vale, Mariana L.; Frota, Nicolly P. R.; Nunes, Nara L. T.; Mariguela, Viviane C.Background: Acupuncture has shown the capability of modulating the immuno-inflammatory response of the host. This study aims to evaluate the effects of electroacupuncture (EA) on ligature-induced periodontitis in rats. Methods: Thirty-two animals were divided into four groups: 1) control; 2) experimental periodontitis (EP); 3) sham-treated (EP/EA-sham); and 4) treated with EA (EP/EA). For the EP groups, a ligat...
Role of NMDA receptors in the trigeminal pathway, and the modulatory effect of ...
Cavalcante, André L. C.; Siqueira, Rafaelly M. P.; Araujo, Joana C. B.; Gondim, Delane V.; Quetz, Josiane S.; Havt, Alexandre; Lima, Aldo A. M.Temporomandibular joint (TMJ) arthritis is a common cause of orofacial pain. In the present study, the modulatory effects of N-methyl-D-aspartate receptors (NMDA-Rs) and magnesium were investigated in TMJ arthritis hypernociception. Male Wistar rats received an intra-articular injection of carrageenan (Cg) in the TMJ, and mechanical hypernociception was measured. The NMDA-R antagonist, MK-801, and magnesium chl...
Oral gabapentin treatment accentuates nerve and peripheralinflammatory response...
Câmara, Carlos C.; Ramos, Heitor F.; Silva, Alan P. da; Araújo, Celina V.; Gomes, Antoniella Souza; Vale, Mariana L.; Barbosa, André Luiz R.Gabapentin (GBP) is an anti-convulsive drug often used as analgesic to control neuropathic pain. Thisstudy aimed at evaluating whether oral GBP treatment could improve nerve inflammation response aftersciatic nerve constriction in association with selected pain and motor spontaneous behavior assessmentsin Wistar rats. We evaluated nerve myeloperoxidase (MPO) and inflammatory cytokines on the 5th daypost-injury,...
Antinociceptive effects of interleukin-4, -10, and -13 on the writhing response...
Vale, Mariana L.; Marques, Jaciara B.; Moreira, Camila A.; Rocha, Francisco Aírton C.; Ferreira, Sérgio H.; Poole, Stephen; Cunha, Fernando Q.The antinociceptive effects of interleukin (IL)-4, -10, and -13 were investigated in two different experimental pain models. Our results showed that pretreatment (30 min) with IL-4 (1–5 ng/animal), IL-10 (0.4–10 ng/animal), or IL-13 (0.4 –2.5 ng/animal) inhibited the writhing response induced by the i.p. administration of acetic acid (53–89%) or zymosan (63–74%) in mice, and the knee joint incapacitation induce...