Introdution: The application of palliative care on children with terminal cancer faces several obstacles by reason of complex symptomatological management. Objectives: This case report aims to describe the experience of the Paediatric Cancer Center in HIAS (Hospital Infantil Albert Sabin) in cases that required palliative sedation, and the elaboration of protocol for indication, practice, and special care in se...
Trata-se de um relato de experiência, cujo objetivo é descrever a experiência do “Jam Sessions”, projeto que desenvolve atividade prazerosa voltada à música, realizado pelos membros do Programa de Educação Tutorial (PET), da faculdade de Medicina da Universidade Federal do Ceará. Embora o objetivo das escolas médicas seja formar profissionais com conhecimentos e habilidades, alguns aspectos dessa formação têm s...
Made available in DSpace on 2019-10-06T16:33:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-10-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico; This study evaluated the participation of CB1 and CB2 receptors in the antiresorptive effect of electroacupuncture (EA) on an experimental model of inflammatory b...
ARAÚJO, Joana Cláudia Bezerra de et al. Inflammatory pain assessment in the arthritis of the temporomandibular joint in rats: a comparison between two phlogistic agents. Journal of Pharmacological and Toxicological Methods, New York, v. 88, p. 100-108, nov. 2017.; Temporomandibular joint (TMJ) disorders are a group of conditions that result in TMJ pain, which frequently limits basic daily activities. Experiment...
ims Ischemia/reperfusion (I/R) injury and metabolic acidosis (MA) are two critical conditions that may simultaneously occur in clinical practice. The result of this combination can be harmful to the kidneys, but this issue has not been thoroughly investigated. The present study evaluated the influence of low systemic pH on various parameters of kidney function in rats that were subjected to an experimental mode...
The systemic administration of lipopolysaccharide (LPS) induces time-dependent behavioral alterations, which are related to sickness behavior and depression. The time-course effects of LPS on prepulse inhibition (PPI) remain unknown. Furthermore, the time-dependent effects of LPS on central nitrite content had not been investigated. Therefore, we studied alterations induced by single LPS (0.5 mg/kg, i.p.) admin...
Background: Oxaliplatin, the third-generation platinum compound, has evolved as one of the most important therapeutic agents in colorectal cancer chemotherapy. The main limiting factor in oxaliplatin treatment is painful neuropathy that is difficult to treat. This side effect has been studied for several years, but its full mechanism is still inconclusive, and effective treatment does not exist. Data suggest th...
The release of cyclo-oxygenase products and sympathomimetic amines, the final mediators of inflammatory pain, is preceded by the generation of pro-inflammatory and nociceptive cytokines by resident cells. Recently drugs such as thalidomide (TALD), pentoxifylline (PTX) and chlorpromazine (CLP), despite of other effects, have been associated with immunomodulatory activity in clinical practice mainly for their mod...
The release of cyclo-oxigenase products and sympathomimetics amines, the final mediators of inflammatory pain, is preceded by the generation of cytokines by resident cells. In recent years a number of cytokines such as IL-4, IL-10, IL-13, IL-6, TGF-β e IFN-α have been described to inhibit the production of TNF-α, IL-1β, IL-6 and IL-8 (cytokines regarded as pró-inflammatory) and possibly to exert their modulator...